Detection of Antibodies to Leptospiral Genus-Specific Antigen in Human and Animal Sera by Indirect Hemagglutination Test with a Partially Purified Genus-Specific Protein Antigen

Noritsugu Sakamoto; Ryo Yanagawa; Etsuro Ono; Hiroshi Kida; Mamoru Mori; Yoshiko Arimitsu; Kiyoto Akama; Jun Yasuda; Kimehiko Too

doi:10.1016/S0176-6724(85)80087-0

Detection of Antibodies to Leptospiral Genus-Specific Antigen in Human and Animal Sera by Indirect Hemagglutination Test with a Partially Purified Genus-Specific Protein Antigen

Noritsugu Sakamoto, Ryo Yanagawa, Etsuro Ono, Hiroshi Kida, Mamoru Mori, Yoshiko Arimitsu, Kiyoto Akama, Jun Yasuda, Kimehiko Too

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Antibodies against leptospiral genus-specific antigen were detected in the sera from clinically diagnosed human leptospirosis and suspected animal leptospirosis by indirect hemagglutination (IHA) test with a partially purified genus-specific protein antigen (GP-Ag). The reaction was positive in the infected humans and animals irrespective of the leptospiral serovars. No significant correlation was found between IHA titer against GP-Ag and microscopic agglutination (MA) titer. IHA titer did not always develop in parallel with MA titers. Sera obtained from healthy individuals were negative in both IHA and MA tests.

Original language	English
Pages (from-to)	548-556
Number of pages	9
Journal	Zentralblatt fur Bakteriologie Mikrobiologie und Hygiene - Abt. 1 Orig. A
Volume	259
Issue number	4
DOIs	https://doi.org/10.1016/S0176-6724(85)80087-0
Publication status	Published - 1985
Externally published	Yes

All Science Journal Classification (ASJC) codes

Immunology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0176-6724(85)80087-0

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Sakamoto, N., Yanagawa, R., Ono, E., Kida, H., Mori, M., Arimitsu, Y., Akama, K., Yasuda, J., & Too, K. (1985). Detection of Antibodies to Leptospiral Genus-Specific Antigen in Human and Animal Sera by Indirect Hemagglutination Test with a Partially Purified Genus-Specific Protein Antigen. Zentralblatt fur Bakteriologie Mikrobiologie und Hygiene - Abt. 1 Orig. A, 259(4), 548-556. https://doi.org/10.1016/S0176-6724(85)80087-0

Detection of Antibodies to Leptospiral Genus-Specific Antigen in Human and Animal Sera by Indirect Hemagglutination Test with a Partially Purified Genus-Specific Protein Antigen. / Sakamoto, Noritsugu; Yanagawa, Ryo; Ono, Etsuro et al.
In: Zentralblatt fur Bakteriologie Mikrobiologie und Hygiene - Abt. 1 Orig. A, Vol. 259, No. 4, 1985, p. 548-556.

Research output: Contribution to journal › Article › peer-review

Sakamoto, N, Yanagawa, R, Ono, E, Kida, H, Mori, M, Arimitsu, Y, Akama, K, Yasuda, J & Too, K 1985, 'Detection of Antibodies to Leptospiral Genus-Specific Antigen in Human and Animal Sera by Indirect Hemagglutination Test with a Partially Purified Genus-Specific Protein Antigen', Zentralblatt fur Bakteriologie Mikrobiologie und Hygiene - Abt. 1 Orig. A, vol. 259, no. 4, pp. 548-556. https://doi.org/10.1016/S0176-6724(85)80087-0

Sakamoto N, Yanagawa R, Ono E, Kida H, Mori M, Arimitsu Y et al. Detection of Antibodies to Leptospiral Genus-Specific Antigen in Human and Animal Sera by Indirect Hemagglutination Test with a Partially Purified Genus-Specific Protein Antigen. Zentralblatt fur Bakteriologie Mikrobiologie und Hygiene - Abt. 1 Orig. A. 1985;259(4):548-556. doi: 10.1016/S0176-6724(85)80087-0

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abstract = "Antibodies against leptospiral genus-specific antigen were detected in the sera from clinically diagnosed human leptospirosis and suspected animal leptospirosis by indirect hemagglutination (IHA) test with a partially purified genus-specific protein antigen (GP-Ag). The reaction was positive in the infected humans and animals irrespective of the leptospiral serovars. No significant correlation was found between IHA titer against GP-Ag and microscopic agglutination (MA) titer. IHA titer did not always develop in parallel with MA titers. Sera obtained from healthy individuals were negative in both IHA and MA tests.",

author = "Noritsugu Sakamoto and Ryo Yanagawa and Etsuro Ono and Hiroshi Kida and Mamoru Mori and Yoshiko Arimitsu and Kiyoto Akama and Jun Yasuda and Kimehiko Too",

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AU - Ono, Etsuro

AU - Kida, Hiroshi

AU - Mori, Mamoru

AU - Arimitsu, Yoshiko

AU - Akama, Kiyoto

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AU - Too, Kimehiko

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AB - Antibodies against leptospiral genus-specific antigen were detected in the sera from clinically diagnosed human leptospirosis and suspected animal leptospirosis by indirect hemagglutination (IHA) test with a partially purified genus-specific protein antigen (GP-Ag). The reaction was positive in the infected humans and animals irrespective of the leptospiral serovars. No significant correlation was found between IHA titer against GP-Ag and microscopic agglutination (MA) titer. IHA titer did not always develop in parallel with MA titers. Sera obtained from healthy individuals were negative in both IHA and MA tests.

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Detection of Antibodies to Leptospiral Genus-Specific Antigen in Human and Animal Sera by Indirect Hemagglutination Test with a Partially Purified Genus-Specific Protein Antigen

Abstract

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UN SDGs

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