Design of vinyl polymers mimicking thermal denaturation of a polypeptide and evaluation as cellular adhesion materials

Suguru Beppu; Takumi Makimura; Takeshi Mori; Keiji Minagawa; Masami Tanaka

Design of vinyl polymers mimicking thermal denaturation of a polypeptide and evaluation as cellular adhesion materials

Suguru Beppu, Takumi Makimura, Takeshi Mori, Keiji Minagawa, Masami Tanaka

Research output: Contribution to conference › Paper › peer-review

Abstract

We synthesized three kinds of α,α-disubstituted vinyl polymers having ester or amide groups (polymer 1, 2, 3), and studied the thermosensitive properties of their aqueous solutions. All of the polymers show phase transition, and 2 and 3 show an unusual thermal hysteresis. It is probably caused by strong hydrogen bonding among the amide groups of polymers. Addition of inorganic salts and urea does not affect this hysteresis. Adhesion of cells to the phase-separated polymer films was investigated.

Original language	English
Pages	5264-5265
Number of pages	2
Publication status	Published - Dec 1 2006
Externally published	Yes
Event	55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan Duration: Sept 20 2006 → Sept 22 2006

Other

Other	55th Society of Polymer Science Japan Symposium on Macromolecules
Country/Territory	Japan
City	Toyama
Period	9/20/06 → 9/22/06

All Science Journal Classification (ASJC) codes

Engineering(all)

Cite this

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title = "Design of vinyl polymers mimicking thermal denaturation of a polypeptide and evaluation as cellular adhesion materials",

abstract = "We synthesized three kinds of α,α-disubstituted vinyl polymers having ester or amide groups (polymer 1, 2, 3), and studied the thermosensitive properties of their aqueous solutions. All of the polymers show phase transition, and 2 and 3 show an unusual thermal hysteresis. It is probably caused by strong hydrogen bonding among the amide groups of polymers. Addition of inorganic salts and urea does not affect this hysteresis. Adhesion of cells to the phase-separated polymer films was investigated.",

author = "Suguru Beppu and Takumi Makimura and Takeshi Mori and Keiji Minagawa and Masami Tanaka",

year = "2006",

month = dec,

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language = "English",

pages = "5264--5265",

note = "55th Society of Polymer Science Japan Symposium on Macromolecules ; Conference date: 20-09-2006 Through 22-09-2006",

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T1 - Design of vinyl polymers mimicking thermal denaturation of a polypeptide and evaluation as cellular adhesion materials

AU - Beppu, Suguru

AU - Makimura, Takumi

AU - Mori, Takeshi

AU - Minagawa, Keiji

AU - Tanaka, Masami

PY - 2006/12/1

Y1 - 2006/12/1

N2 - We synthesized three kinds of α,α-disubstituted vinyl polymers having ester or amide groups (polymer 1, 2, 3), and studied the thermosensitive properties of their aqueous solutions. All of the polymers show phase transition, and 2 and 3 show an unusual thermal hysteresis. It is probably caused by strong hydrogen bonding among the amide groups of polymers. Addition of inorganic salts and urea does not affect this hysteresis. Adhesion of cells to the phase-separated polymer films was investigated.

AB - We synthesized three kinds of α,α-disubstituted vinyl polymers having ester or amide groups (polymer 1, 2, 3), and studied the thermosensitive properties of their aqueous solutions. All of the polymers show phase transition, and 2 and 3 show an unusual thermal hysteresis. It is probably caused by strong hydrogen bonding among the amide groups of polymers. Addition of inorganic salts and urea does not affect this hysteresis. Adhesion of cells to the phase-separated polymer films was investigated.

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UR - http://www.scopus.com/inward/citedby.url?scp=33846182310&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:33846182310

SP - 5264

EP - 5265

T2 - 55th Society of Polymer Science Japan Symposium on Macromolecules

Y2 - 20 September 2006 through 22 September 2006

ER -

Design of vinyl polymers mimicking thermal denaturation of a polypeptide and evaluation as cellular adhesion materials

Abstract

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All Science Journal Classification (ASJC) codes

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