Deletion in the 190 kDa antigen gene repeat region of Rickettsia rickettsii

Mitsuru Matsumoto, Yoshiki Tange, Takanori Okada, Yasuhiro Inoue, Takahiko Horiuchi, Yuzuru Kobayashi, Shigeru Fujita

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


The 190 kDa outer membrane protein of Rickettsia rickettsii is a major immunodominant protective antigen which contains 13 tandem nearly identical repeating sequences. We have identified a deletion in the 190 kDa antigen gene of R. rickettsii strain Smith maintained in the laboratory. The deletion occurred within the repeat region of this gene and the mutated repeat region corresponded to one repeating unit in size.

Original languageEnglish
Pages (from-to)57-62
Number of pages6
JournalMicrobial Pathogenesis
Issue number1
Publication statusPublished - Jan 1996

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Infectious Diseases


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