Degradation of the endoplasmic reticulum–anchored transcription factor MyRF by the ubiquitin ligase SCF^Fbxw7 in a manner dependent on the kinase GSK-3

Biochemistry, Genetics and Molecular Biology

• Regulatory Mechanism 100%
• Myelin 91%
• Ubiquitination 25%
• Glycogen Synthase Kinase 3 25%
• Degradation 16%
• Nested Gene 16%
• Transcription Factor 16%
• Ubiquitin Ligase 16%
• F-Box Protein 16%
• Kinase 8%
• Electric Potential 8%
• Transcription 8%
• Protein 8%
• Mouse 8%
• Messenger RNA 8%
• Phosphorylation 8%
• N-Terminus 8%
• Mutation 8%
• Immunoprecipitation 8%
• RNA Sequence 8%
• Ubiquitin 8%
• Proteasome 8%
• Protein Subunit 8%
• C2C12 8%
• Myelination 8%
• Protein Stability 8%