Deep eutectic solvents as promising green solvents in dispersive liquid–liquid microextraction based on solidification of floating organic droplet: Recent applications, challenges and future perspectives

Asmaa Kamal El-Deen, Kuniyoshi Shimizu

Research output: Contribution to journalReview articlepeer-review

23 Citations (Scopus)

Abstract

Deep eutectic solvents (DESs) have recently attracted attention as a promising green alternative to conventional hazardous solvents by virtue of their simple preparation, low cost, and biodegradability. Even though the application of DESs in analytical chemistry is still in its early stages, the number of publications on this topic is growing. Analytical procedures applying dispersive liquid–liquid microextraction based on the solidification of floating organic droplets (DLLME-SFOD) are among the more appealing approaches where DESs have been found to be applicable. Herein, we provide a summary of the articles that are concerned with the application of DESs in the DLLME-SFOD of target analytes from diverse samples to provide up-to-date knowledge in this area. In addition, the major variables influencing enrichment efficiency and the microextraction mechanism are fully investigated and explained. Finally, the challenges and future perspectives of applying DESs in DLLME-SFOD are thoroughly discussed and are critically analyzed.

Original languageEnglish
Article number7406
JournalMolecules
Volume26
Issue number23
DOIs
Publication statusPublished - Dec 1 2021

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Chemistry (miscellaneous)
  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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