D-amino acids in mammals and their diagnostic value

Kenji Hamase, Akiko Morikawa, Kiyoshi Zaitsu

Research output: Contribution to journalReview articlepeer-review

196 Citations (Scopus)


Substantial amounts of D-amino acids are present in mammalian tissues; their function, origin and relationship between pathophysiological processes have been of great interest over the last two decades. In the present article, analytical methods including chromatographic, electrophoretic and enzymatic methods to determine D-amino acids in mammalian tissues are reviewed, and the distribution of these D-amino acids in mammals is discussed. An overview of the function, origin and relationship between the amino acids and pathophysiological processes is also given.

Original languageEnglish
Pages (from-to)73-91
Number of pages19
JournalJournal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
Issue number1-2
Publication statusPublished - Dec 5 2002

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Clinical Biochemistry
  • Cell Biology


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