Cytotoxic lavandulyl flavanones from Sophora flavescens

Tai Hyun Kang, Sei Joon Jeong, Won Gil Ko, Na Young Kim, Byung Hoon Lee, Masanori Inagaki, Tomofumi Miyamoto, Ryuichi Higuchi, Youn Chul Kim

Research output: Contribution to journalArticlepeer-review

126 Citations (Scopus)


Two new lavandulylated flavanones, (2S)-2'-methoxykurarinone (1) and (- )-kurarinone (2), were isolated from the root of Sophora flavescens, together with two known lavandulyl flavanones, sophoraflavanone G (3) and leachianone A (4), and two known isoflavonoids, formononetin and l-maakiain. The structures of 1 and 2 were determined on the basis of optical rotation and spectral evidence and by comparison with known compounds. Compounds 1-4 exhibited cytotoxic activity against human myeloid leukemia HL-60 cells.

Original languageEnglish
Pages (from-to)680-681
Number of pages2
JournalJournal of Natural Products
Issue number5
Publication statusPublished - May 2000

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry


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