Cushing’s syndrome and psychosis: A case report and literature review

Yuka Fujii; Yoshito Mizoguchi; Jun Masuoka; Yayoi Matsuda; Tatsuya Abe; Keizo Anzai; Yutaka Kunitake; Hiroshi Tateishi; Takayoshi Inaba; Toru Murakawa; Takahiro A. Kato; Akira Monji

doi:10.4088/PCC.18br02279

Cushing’s syndrome and psychosis: A case report and literature review

Yuka Fujii, Yoshito Mizoguchi, Jun Masuoka, Yayoi Matsuda, Tatsuya Abe, Keizo Anzai, Yutaka Kunitake, Hiroshi Tateishi, Takayoshi Inaba, Toru Murakawa, Takahiro A. Kato, Akira Monji

Neuro-Psychiatry

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Psychiatric complications of Cushing’s syndrome include irritability, anxiety, depressed mood, and cognitive impairment. Psychosis is a rare manifestation of Cushing’s syndrome; therefore, the literature on the subject is limited and consists mainly of clinical case reports. We report a case of Cushing’s syndrome misdiagnosed as schizophrenia-like psychosis for more than 10 years. Transsphenoidal adenomectomy resulted in amelioration of psychiatric symptoms as well as improvement of cognitive ability. Clinicians should consider the presence of psychiatric symptoms predating the diagnosis of Cushing’s syndrome, especially when these symptoms are persistent and treatment-resistant, as seen in the present case.

Original language	English
Article number	18br02279
Journal	Primary Care Companion to the Journal of Clinical Psychiatry
Volume	20
Issue number	5
DOIs	https://doi.org/10.4088/PCC.18br02279
Publication status	Published - 2018

All Science Journal Classification (ASJC) codes

Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.4088/PCC.18br02279

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abstract = "Psychiatric complications of Cushing{\textquoteright}s syndrome include irritability, anxiety, depressed mood, and cognitive impairment. Psychosis is a rare manifestation of Cushing{\textquoteright}s syndrome; therefore, the literature on the subject is limited and consists mainly of clinical case reports. We report a case of Cushing{\textquoteright}s syndrome misdiagnosed as schizophrenia-like psychosis for more than 10 years. Transsphenoidal adenomectomy resulted in amelioration of psychiatric symptoms as well as improvement of cognitive ability. Clinicians should consider the presence of psychiatric symptoms predating the diagnosis of Cushing{\textquoteright}s syndrome, especially when these symptoms are persistent and treatment-resistant, as seen in the present case.",

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AU - Fujii, Yuka

AU - Mizoguchi, Yoshito

AU - Masuoka, Jun

AU - Matsuda, Yayoi

AU - Abe, Tatsuya

AU - Anzai, Keizo

AU - Kunitake, Yutaka

AU - Tateishi, Hiroshi

AU - Inaba, Takayoshi

AU - Murakawa, Toru

AU - Kato, Takahiro A.

AU - Monji, Akira

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AB - Psychiatric complications of Cushing’s syndrome include irritability, anxiety, depressed mood, and cognitive impairment. Psychosis is a rare manifestation of Cushing’s syndrome; therefore, the literature on the subject is limited and consists mainly of clinical case reports. We report a case of Cushing’s syndrome misdiagnosed as schizophrenia-like psychosis for more than 10 years. Transsphenoidal adenomectomy resulted in amelioration of psychiatric symptoms as well as improvement of cognitive ability. Clinicians should consider the presence of psychiatric symptoms predating the diagnosis of Cushing’s syndrome, especially when these symptoms are persistent and treatment-resistant, as seen in the present case.

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Cushing’s syndrome and psychosis: A case report and literature review

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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