Crystallization and preliminary crystallographic study of DNA polymerase from Pyrococcus furiosus

Hirokazu Nishida, Maiko Tanabe, Yoshizumi Ishino, Takuji Oyama, Kosuke Morikawa

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

A new member of archaeal DNA polymerase from Pyrococcus furiosus was crystallized. Diffraction data to 3.1 Å of the selenomethionine- derivatized crystal were collected, and preliminary crystallographic study has been completed. The crystal belongs to the space group C2 with unit cell parameters of a = 93.2 Å, b = 124.9 Å, c = 87.7 Å, α = 90° , β = 109.7° , and γ = 90°. Assuming the presence of one molecule in the asymmetric unit, the solvent content of the crystal is estimated to be 54%, corresponding to a Matthews coefficient VM of 2.7Å3 Da-1.

Original languageEnglish
Pages (from-to)403-405
Number of pages3
JournalProtein and Peptide Letters
Volume14
Issue number4
DOIs
Publication statusPublished - Apr 2007

All Science Journal Classification (ASJC) codes

  • Structural Biology
  • Biochemistry

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