We report the cases of Crohn's disease in siblings. Both of these brothers genetically had B 51 in their HLA, and psychologically they had workaholic life styles and over-adaptative characters in their workplaces and homes. We found the onset and clinical course of this disease were affected by psychosomatic factors rather than by genetic factors, and psychosomatic approaches were clinically effective in treating patients with Crohn's disease.
|Number of pages
|Japanese Journal of Psychosomatic Medicine
|Published - 1999
All Science Journal Classification (ASJC) codes
- Psychiatry and Mental health