TY - GEN
T1 - Continuous generation of cell-laden microgels through deterministic lateral displacement arrays
AU - Tottori, Naotomo
AU - Nisisako, Takasi
N1 - Funding Information:
This work was supported by JSPS KAKENHI Grant Number 19K23585.
Publisher Copyright:
© 2020 CBMS-0001
PY - 2020
Y1 - 2020
N2 - We report a novel microfluidic approach for continuous generation of cell-laden microgels using a deterministic lateral displacement (DLD) array that enable on-chip separation, reaction and extraction of microgels from the oil into aqueous phase continuously. Spherical cell-laden Ca-alginate microgel particles dispersed in aqueous phase without satellite droplets were obtained by transporting Na-alginate main droplets across the streams of the CaCl2 emulsion and glycerol aqueous solution through the DLD pillar arrays.
AB - We report a novel microfluidic approach for continuous generation of cell-laden microgels using a deterministic lateral displacement (DLD) array that enable on-chip separation, reaction and extraction of microgels from the oil into aqueous phase continuously. Spherical cell-laden Ca-alginate microgel particles dispersed in aqueous phase without satellite droplets were obtained by transporting Na-alginate main droplets across the streams of the CaCl2 emulsion and glycerol aqueous solution through the DLD pillar arrays.
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M3 - Conference contribution
AN - SCOPUS:85098269595
T3 - MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
SP - 108
EP - 109
BT - MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PB - Chemical and Biological Microsystems Society
T2 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020
Y2 - 4 October 2020 through 9 October 2020
ER -