Complete response in a case of anastomotic recurrence of rectal cancer treated with S-1 monotherapy

Akira Kabashima, Dai Kitagawa, Toshihiko Nakamura, Naoko Kondo, Seiichi Teramoto, Genkichi Saito, Tomoru Funahashi, Eisuke Adachi, Yoichi Ikeda

Research output: Contribution to journalArticlepeer-review


A 63-year-old woman underwent a low anterior resection for rectal cancer in 2002.A n anastomotic recurrence was diagnosed in July 2011.S he rejected the possibility of colostomy as radical surgery.Chemotherapy consisting of capecitabine+ oxaliplatin (XELOX) or folinic acid, fluorouracil, and oxaliplatin (FOLFOX6) + bevacizumab were not possible because of high costs. In view of the lower costs and the potential for ambulation, S-1 monotherapy was started. After 3 months, a reduction in the recurrent lesion was observed.After 19 months, the recurrent lesion revealed a scar, which was judged by biopsy to be Group 1.We had achieved a pathological complete response (CR).The standard treatment for recurrent colon cancer is surgical resection or multidrug chemotherapy. However, in view of a patient's quality of life (QOL), S-1 monotherapy may be considered as a potential therapy.

Original languageEnglish
Pages (from-to)1716-1718
Number of pages3
JournalGan to kagaku ryoho. Cancer & chemotherapy
Issue number12
Publication statusPublished - Nov 1 2014

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research


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