Clinicopathological features of hemorrhagic gastrointestinal stromal tumor

Kei Sakamoto, Kazuoki Hizawa, Kouhei Fujita, Masashi Kameda, Hiroyuki Hamada, Katsuki Okamura, Fumiyoshi Fushimi, Takehiro Torisu

Research output: Contribution to journalArticlepeer-review


In order to demonstrate the bleeding risk factors of GIST (gastrointestinal stromal tumor), we retrospectively investigated clinicopathological features between hemorrhagic (H group, 24 cases) and nonhemorrhagic GIST (NH group, 30 cases). In addition, we investigated features between the E group (6 cases) necessitating TAE (trans-catheter arterial embolization) and NE group (other 48 cases). Whereas H group partly includes high-risk grade GIST with chronic bleeding, meanwhile the E group (reflecting acute bleeding) is characterized by a highly enhanced mass with ulceration, comprising of smaller low-risk grade GIST. Amongst the 29 cases for forceps biopsy, which were 6 cases (21%) including one of E group, needed be hospitalized for postbiopsy bleeding. Acute bleeding in GIST may not be associated with malignant transformation. Postbiopsy bleeding or massive hemorrhage can also be encountered particularly in highly enhanced GIST with ulceration, even with a small and low-risk grade.

Original languageEnglish
Pages (from-to)888-895
Number of pages8
JournalJournal of Japanese Society of Gastroenterology
Issue number10
Publication statusPublished - Oct 10 2020

All Science Journal Classification (ASJC) codes

  • Gastroenterology


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