Clinicopathological feature and long-term prognosis of apocrine carcinoma of the breast in Japanese women

Hideya Takeuchi, Kohichi Tsuji, Hiroaki Ueo, Tadashi Kano, Yoshihiko Maehara

Research output: Contribution to journalReview articlepeer-review

32 Citations (Scopus)


Because of the rarity of apocrine carcinoma and lack of standardized criteria for the diagnosis, the definitive conclusions of clinicopathologic features and the prognosis has not been determined. We retrospectively examined data on 2091 curatively treated Japanese patients with primary breast carcinoma. Among them, 33 (1.6%) who had been diagnosed of apocrine carcinoma were reviewed. Compared with non-apocrine carcinoma, apocrine carcinoma was characterized by less positive rates of ER and PR, and by frequent rates of unilateral multicentric breast carcinoma with significant difference. The clinicopathological factors influencing 12-year survival rate were lymph node metastasis, lymphatic involvement and vascular involvement. There was no difference in survival rates at 10 years after operation between apocrine carcinoma and non-apocrine carcinoma. Our result shows unique hormone response and unilateral multicentricity are only typical clinicopathological features of apocrine carcinoma.

Original languageEnglish
Pages (from-to)49-54
Number of pages6
JournalBreast Cancer Research and Treatment
Issue number1
Publication statusPublished - Nov 2004

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research


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