Abstract
An Abelson virus-transformed murine pre-B cell line class-switched from μ to γ3 or γ2b at the pre-b stage during culture. A class-swtich was mediated by the deletion mechanism of the intervening C(H) genes on the active chromosome. This study showed for the first time that class-switching at the pre-B cell stage was not always confined to γ2b production.
| Original language | English |
|---|---|
| Pages (from-to) | 3092-3097 |
| Number of pages | 6 |
| Journal | Journal of Immunology |
| Volume | 136 |
| Issue number | 8 |
| Publication status | Published - Jan 1 1986 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Immunology and Allergy
- Immunology