TY - GEN
T1 - Christmas-tree nanowire chips for dna separation
AU - Rahong, Sakon
AU - Yasui, Takao
AU - Yanagida, Takeshi
AU - Kanai, Masaki
AU - Nagashima, Kazuki
AU - Klamchuen, Annop
AU - Gang, Meng
AU - Yong, He
AU - Zhuge, Fuwei
AU - Kaji, Noritada
AU - Baba, Yoshinobu
AU - Kawai, Tomoji
PY - 2013
Y1 - 2013
N2 - We demonstrated the DNA separation by using the three dimensional Christmas-tree nanowire chips embedded in the microfluidic system to enhance the separation range and decrease the time consuming also. We synthesize the Christmas-tree nanowire by decorating Au catalyst along the nanowires structure by sputtering and growing the branch of nanowires by Vapor-Liquid-Solid (VLS) technique as a cycle. The DNA electrophoretic mobility in the Christmas- tree nanowire decreases when the pore size between nanowire decreases by growth time. The DNA migration in the Christmas-tree nanowire chip is faster than gel electrophoresis due to the rigidity of 3D nanowire structure. Consequently, we succeeded to separate the wide range of DNA molecules by mobility difference in 3D nanowire structure in short time.
AB - We demonstrated the DNA separation by using the three dimensional Christmas-tree nanowire chips embedded in the microfluidic system to enhance the separation range and decrease the time consuming also. We synthesize the Christmas-tree nanowire by decorating Au catalyst along the nanowires structure by sputtering and growing the branch of nanowires by Vapor-Liquid-Solid (VLS) technique as a cycle. The DNA electrophoretic mobility in the Christmas- tree nanowire decreases when the pore size between nanowire decreases by growth time. The DNA migration in the Christmas-tree nanowire chip is faster than gel electrophoresis due to the rigidity of 3D nanowire structure. Consequently, we succeeded to separate the wide range of DNA molecules by mobility difference in 3D nanowire structure in short time.
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M3 - Conference contribution
AN - SCOPUS:84907316622
SN - 9781632666246
T3 - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
SP - 164
EP - 166
BT - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PB - Chemical and Biological Microsystems Society
T2 - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Y2 - 27 October 2013 through 31 October 2013
ER -