Chirality sensing by nonchiral porphines

Jan Labuta, Shinsuke Ishihara, Atsuomi Shundo, Satoshi Arai, Shinji Takeoka, Katsuhiko Ariga, Jonathan P. Hill

Research output: Contribution to journalArticlepeer-review

36 Citations (Scopus)


Let's split the difference: Nonchiral porphine macrocycles have been used as chemical shift agents for the determination of the enantiomeric excesses of chiral carboxylic acids. This method is based on the observation of the relative splitting induced in the 1H NMR resonances of the porphine protons. A mechanism for the recognition based on the fast exchange of the guest molecules has been proposed (see scheme).

Original languageEnglish
Pages (from-to)3558-3561
Number of pages4
JournalChemistry - A European Journal
Issue number13
Publication statusPublished - Mar 21 2011

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • Catalysis
  • Organic Chemistry


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