Chemoselective hydrogenation of imides catalyzed by Cp*Ru(PN) complexes and its application to the asymmetric synthesis of paroxetine

Masato Ito; Ayaka Sakaguchi; Chika Kobayashi; Takao Ikariya

doi:10.1021/ja067777y

Chemoselective hydrogenation of imides catalyzed by Cp*Ru(PN) complexes and its application to the asymmetric synthesis of paroxetine

Masato Ito, Ayaka Sakaguchi, Chika Kobayashi, Takao Ikariya

Research output: Contribution to journal › Article › peer-review

155 Citations (Scopus)

Abstract

This work represents the first catalytic hydrogenation of imides into amides and primary alcohols, in which the unique chemoselectivity is originated from the bifunctional nature of ruthenium-NH moiety in the catalyst.

Original language	English
Pages (from-to)	290-291
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	129
Issue number	2
DOIs	https://doi.org/10.1021/ja067777y
Publication status	Published - Jan 17 2007
Externally published	Yes

All Science Journal Classification (ASJC) codes

Catalysis
Chemistry(all)
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja067777y

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abstract = "This work represents the first catalytic hydrogenation of imides into amides and primary alcohols, in which the unique chemoselectivity is originated from the bifunctional nature of ruthenium-NH moiety in the catalyst.",

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AU - Ito, Masato

AU - Sakaguchi, Ayaka

AU - Kobayashi, Chika

AU - Ikariya, Takao

PY - 2007/1/17

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Chemoselective hydrogenation of imides catalyzed by Cp*Ru(PN) complexes and its application to the asymmetric synthesis of paroxetine

Abstract

All Science Journal Classification (ASJC) codes

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