Chemical pneumonitis and acute lung injury caused by inhalation of nickel fumes

Kei Kunimasa, Machiko Arita, Hiromasa Tachibana, Kazuya Tsubouchi, Satoshi Konishi, Yohei Korogi, Akihiro Nishiyama, Tadashi Ishida

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


A 50-year-old man with a 30-year occupational history of welding presented with low-grade fever, fatigue and persistent dry cough. Computed tomography (CT) of the chest revealed interlobular septal thickening and bilateral non-segmental patchy ground-glass opacities except in the sub-pleural zone. He revealed that he had inhaled nickel fumes 3 days previously at work. These findings suggested a diagnosis of pneumonitis induced by inhalation of nickel fumes. Fewer reports describe pneumonitis associated with the inhalation of nickel compared with zinc fumes. Although nickel compounds are particularly pernicious among the transition metals and more toxic than zinc compounds, nickel fume inhalation rarely induces lethal acute respiratory distress syndrome. Our patient was successfully treated with corticosteroid.

Original languageEnglish
Pages (from-to)2035-2038
Number of pages4
JournalInternal Medicine
Issue number18
Publication statusPublished - 2011
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Internal Medicine


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