TY - JOUR
T1 - Characterization of socioeconomic status of Japanese patients with atopic dermatitis showing poor medical adherence and reasons for drug discontinuation
AU - Murota, Hiroyuki
AU - Takeuchi, Satoshi
AU - Sugaya, Makoto
AU - Tanioka, Miki
AU - Onozuka, Daisuke
AU - Hagihara, Akihito
AU - Saeki, Hidehisa
AU - Imafuku, Shinichi
AU - Abe, Masatoshi
AU - Shintani, Yoichi
AU - Kaneko, Sakae
AU - Masuda, Koji
AU - Hiragun, Takaaki
AU - Inomata, Naoko
AU - Kitami, Yuki
AU - Tsunemi, Yuichiro
AU - Abe, Shinya
AU - Kobayashi, Miwa
AU - Morisky, Donald E.
AU - Furue, Masutaka
AU - Katoh, Norihito
N1 - Funding Information:
This study was financially supported by Mitsubishi Tanabe Pharma Corporation.
Publisher Copyright:
© 2015 Z.
PY - 2015/9
Y1 - 2015/9
N2 - Background: Patients' high adherence to medication is indispensable for the management of skin diseases including atopic dermatitis. We previously showed poor medication adherence in Japanese dermatological patients. Objective: This study was conducted to determine the level of adherence to oral or topical medication in Japanese patients with atopic dermatitis, attempting to characterize the socioeconomic status of those patients with poor adherence. Methods: A web questionnaire survey on demographic data as well as adherence level was conducted on patients registered in the monitoring system. Adherence level was assessed with Morisky Medication Adherence Scale-8 (MMAS-8). Among a total of 3096 respondents with dermatological disorders, data of 1327 subjects with atopic dermatitis were extracted and analyzed. Results: More than 80% of subjects felt that both oral and topical medications were safe and efficacious, while less than 60% of them were satisfied with their treatment. Levels of adherence to oral and topical treatments were evaluated with MMAS-8, giving scores of 4.6 and 4.2, respectively. Demographic factors such as gender, marital status, state of employment, alcohol consumption, frequency of hospital visits, and experience of drug effectiveness had a significant impact on the degree of adherence to treatment. Conclusion: Medication adherence level in Japanese subjects with atopic dermatitis was relatively low compared with that of other chronic diseases. Our survey has characterized patients with poor adherence, who are good targets for interventions to maximize potentially limited healthcare resources.
AB - Background: Patients' high adherence to medication is indispensable for the management of skin diseases including atopic dermatitis. We previously showed poor medication adherence in Japanese dermatological patients. Objective: This study was conducted to determine the level of adherence to oral or topical medication in Japanese patients with atopic dermatitis, attempting to characterize the socioeconomic status of those patients with poor adherence. Methods: A web questionnaire survey on demographic data as well as adherence level was conducted on patients registered in the monitoring system. Adherence level was assessed with Morisky Medication Adherence Scale-8 (MMAS-8). Among a total of 3096 respondents with dermatological disorders, data of 1327 subjects with atopic dermatitis were extracted and analyzed. Results: More than 80% of subjects felt that both oral and topical medications were safe and efficacious, while less than 60% of them were satisfied with their treatment. Levels of adherence to oral and topical treatments were evaluated with MMAS-8, giving scores of 4.6 and 4.2, respectively. Demographic factors such as gender, marital status, state of employment, alcohol consumption, frequency of hospital visits, and experience of drug effectiveness had a significant impact on the degree of adherence to treatment. Conclusion: Medication adherence level in Japanese subjects with atopic dermatitis was relatively low compared with that of other chronic diseases. Our survey has characterized patients with poor adherence, who are good targets for interventions to maximize potentially limited healthcare resources.
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U2 - 10.1016/j.jdermsci.2015.05.010
DO - 10.1016/j.jdermsci.2015.05.010
M3 - Article
C2 - 26255207
AN - SCOPUS:84945479597
SN - 0923-1811
VL - 79
SP - 279
EP - 287
JO - Journal of Dermatological Science
JF - Journal of Dermatological Science
IS - 3
ER -