Cerebrospinal fluid proteomics exerts predictive potential for immune effector cell-associated neurotoxicity syndrome (ICANS) in CAR-T cell therapy

Tomoko Nomiyama; Daiki Setoyama; Ikumi Yamanaka; Masatoshi Shimo; Kohta Miyawaki; Takuji Yamauchi; Fumiaki Jinnouchi; Teppei Sakoda; Kensuke Sasaki; Takahiro Shima; Yoshikane Kikushige; Yasuo Mori; Koichi Akashi; Koji Kato; Yuya Kunisaki

doi:10.1038/s41375-025-02541-6

Cerebrospinal fluid proteomics exerts predictive potential for immune effector cell-associated neurotoxicity syndrome (ICANS) in CAR-T cell therapy

Research output: Contribution to journal › Letter › peer-review

Original language	English
Pages (from-to)	983-987
Number of pages	5
Journal	Leukemia
Volume	39
Issue number	4
DOIs	https://doi.org/10.1038/s41375-025-02541-6
Publication status	Published - Apr 2025

All Science Journal Classification (ASJC) codes

Hematology
Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/s41375-025-02541-6

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Nomiyama, T., Setoyama, D., Yamanaka, I., Shimo, M., Miyawaki, K., Yamauchi, T., Jinnouchi, F., Sakoda, T., Sasaki, K., Shima, T., Kikushige, Y., Mori, Y., Akashi, K., Kato, K., & Kunisaki, Y. (2025). Cerebrospinal fluid proteomics exerts predictive potential for immune effector cell-associated neurotoxicity syndrome (ICANS) in CAR-T cell therapy. Leukemia, 39(4), 983-987. https://doi.org/10.1038/s41375-025-02541-6

Nomiyama, T, Setoyama, D , Yamanaka, I, Shimo, M, Miyawaki, K , Yamauchi, T , Jinnouchi, F , Sakoda, T, Sasaki, K, Shima, T, Kikushige, Y , Mori, Y , Akashi, K , Kato, K & Kunisaki, Y 2025, 'Cerebrospinal fluid proteomics exerts predictive potential for immune effector cell-associated neurotoxicity syndrome (ICANS) in CAR-T cell therapy', Leukemia, vol. 39, no. 4, pp. 983-987. https://doi.org/10.1038/s41375-025-02541-6

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title = "Cerebrospinal fluid proteomics exerts predictive potential for immune effector cell-associated neurotoxicity syndrome (ICANS) in CAR-T cell therapy",

author = "Tomoko Nomiyama and Daiki Setoyama and Ikumi Yamanaka and Masatoshi Shimo and Kohta Miyawaki and Takuji Yamauchi and Fumiaki Jinnouchi and Teppei Sakoda and Kensuke Sasaki and Takahiro Shima and Yoshikane Kikushige and Yasuo Mori and Koichi Akashi and Koji Kato and Yuya Kunisaki",

year = "2025",

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doi = "10.1038/s41375-025-02541-6",

language = "English",

volume = "39",

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T1 - Cerebrospinal fluid proteomics exerts predictive potential for immune effector cell-associated neurotoxicity syndrome (ICANS) in CAR-T cell therapy

AU - Nomiyama, Tomoko

AU - Setoyama, Daiki

AU - Yamanaka, Ikumi

AU - Shimo, Masatoshi

AU - Miyawaki, Kohta

AU - Yamauchi, Takuji

AU - Jinnouchi, Fumiaki

AU - Sakoda, Teppei

AU - Sasaki, Kensuke

AU - Shima, Takahiro

AU - Kikushige, Yoshikane

AU - Mori, Yasuo

AU - Akashi, Koichi

AU - Kato, Koji

AU - Kunisaki, Yuya

PY - 2025/4

Y1 - 2025/4

UR - https://www.scopus.com/pages/publications/105000356809

UR - https://www.scopus.com/pages/publications/105000356809#tab=citedBy

U2 - 10.1038/s41375-025-02541-6

DO - 10.1038/s41375-025-02541-6

M3 - Letter

C2 - 40065076

AN - SCOPUS:105000356809

SN - 0887-6924

VL - 39

SP - 983

EP - 987

JO - Leukemia

JF - Leukemia

IS - 4

ER -

Cerebrospinal fluid proteomics exerts predictive potential for immune effector cell-associated neurotoxicity syndrome (ICANS) in CAR-T cell therapy

All Science Journal Classification (ASJC) codes

UN SDGs

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