Cement leakage during vertebroplasty can be predicted on preoperative MRI

Akio Hiwatashi, Yoshimitsu Ohgiya, Naoya Kakimoto, Per Lennart Westesson

Research output: Contribution to journalReview articlepeer-review

34 Citations (Scopus)


OBJECTIVE. Previous studies have shown that cement leakage into an adjacent disk space is a risk factor for new fracture after vertebroplasty. The purpose of this study was to investigate the use of preoperative MRI for predicting such cement leakage. MATERIALS AND METHODS. Our institutional review board approved this retrospective study and waived the requirement of informed consent. We studied preoperative MRI of 46 vertebroplasty patients (107 vertebral bodies). Endplate cortical defect, abnormal T2 hyperintensity in adjacent disk space, intravertebral cleft, degree of compression, and wedge angle were correlated to the incidence of cement leakage into the adjacent disk. Patient age, sex, and location of treated vertebral body were also evaluated. We used logistic regression analysis and Fisher's exact probability test to analyze the association between cement leakage and these observations. RESULTS. Cortical defect in the endplate of the treated vertebral body, abnormal T2 hyperintensity in the adjacent intervertebral disk, and absence of intravertebral cleft were associated with cement leakage into the disk space (p > 0.05). There was no statistically significant association between cement leakage into the disk and degree of compression, wedge angle, location of treated vertebral body, patient age, or sex (p > 0.05). CONCLUSION. Cement leakage into an adjacent disk is more common when there is a cortical defect in the endplate and increased T2 signal in the adjacent disk and is less common if there is an intravertebral cleft.

Original languageEnglish
Pages (from-to)1089-1093
Number of pages5
JournalAmerican Journal of Roentgenology
Issue number4
Publication statusPublished - Apr 2007

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging


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