TY - JOUR
T1 - Catalytic Asymmetric Hydrogenation of Heteroarenes and Arenes
AU - Kuwano, Ryoichi
N1 - Publisher Copyright:
Copyright © 2015 Taylor & Francis Group, LLC.
PY - 2015/6/3
Y1 - 2015/6/3
N2 - A trans-chelating chiral bisphosphine, PhTRAP, allows the ruthenium-catalyzed hydrogenation of various azoles to proceed with high enantioselectivity. The PhTRAP-ruthenium catalyst transformed indoles, pyrroles, imidazoles, and oxazoles into the corresponding chiral heterocycles. Naphthalenes are also reduced with hydrogen by the chiral ruthenium catalyst, exclusively giving tetralins. Some 2-alkoxytetralins were obtained with over 90% ee from the catalytic asymmetric hydrogenation of the corresponding substituted naphthalenes.
AB - A trans-chelating chiral bisphosphine, PhTRAP, allows the ruthenium-catalyzed hydrogenation of various azoles to proceed with high enantioselectivity. The PhTRAP-ruthenium catalyst transformed indoles, pyrroles, imidazoles, and oxazoles into the corresponding chiral heterocycles. Naphthalenes are also reduced with hydrogen by the chiral ruthenium catalyst, exclusively giving tetralins. Some 2-alkoxytetralins were obtained with over 90% ee from the catalytic asymmetric hydrogenation of the corresponding substituted naphthalenes.
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U2 - 10.1080/10426507.2014.974752
DO - 10.1080/10426507.2014.974752
M3 - Article
AN - SCOPUS:84953931839
SN - 1042-6507
VL - 190
SP - 715
EP - 719
JO - Phosphorus, Sulfur and Silicon and the Related Elements
JF - Phosphorus, Sulfur and Silicon and the Related Elements
IS - 5-6
ER -