Catalytic asymmetric addition of organolithiums to aldimines

Kiyoshi Tomioka; Isao Inoue; Mitsuru Shindo; Kenji Koga

doi:10.1016/0040-4039(91)80698-6

Catalytic asymmetric addition of organolithiums to aldimines

Kiyoshi Tomioka, Isao Inoue, Mitsuru Shindo, Kenji Koga

Research output: Contribution to journal › Article › peer-review

87 Citations (Scopus)

Abstract

An asymmetric 1,2-addition of organolithiums to imines (1) was catalyzed by a substoichiometric amount (0.05-0.3 equivalent) of a chiral aminoether (2) to provide the corresponding optically active amines (3).

Original language	English
Pages (from-to)	3095-3098
Number of pages	4
Journal	Tetrahedron Letters
Volume	32
Issue number	26
DOIs	https://doi.org/10.1016/0040-4039(91)80698-6
Publication status	Published - Jun 24 1991
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/0040-4039(91)80698-6

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title = "Catalytic asymmetric addition of organolithiums to aldimines",

abstract = "An asymmetric 1,2-addition of organolithiums to imines (1) was catalyzed by a substoichiometric amount (0.05-0.3 equivalent) of a chiral aminoether (2) to provide the corresponding optically active amines (3).",

author = "Kiyoshi Tomioka and Isao Inoue and Mitsuru Shindo and Kenji Koga",

year = "1991",

month = jun,

day = "24",

doi = "10.1016/0040-4039(91)80698-6",

language = "English",

volume = "32",

pages = "3095--3098",

journal = "Tetrahedron Letters",

issn = "0040-4039",

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T1 - Catalytic asymmetric addition of organolithiums to aldimines

AU - Tomioka, Kiyoshi

AU - Inoue, Isao

AU - Shindo, Mitsuru

AU - Koga, Kenji

PY - 1991/6/24

Y1 - 1991/6/24

N2 - An asymmetric 1,2-addition of organolithiums to imines (1) was catalyzed by a substoichiometric amount (0.05-0.3 equivalent) of a chiral aminoether (2) to provide the corresponding optically active amines (3).

AB - An asymmetric 1,2-addition of organolithiums to imines (1) was catalyzed by a substoichiometric amount (0.05-0.3 equivalent) of a chiral aminoether (2) to provide the corresponding optically active amines (3).

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U2 - 10.1016/0040-4039(91)80698-6

DO - 10.1016/0040-4039(91)80698-6

M3 - Article

AN - SCOPUS:0025728076

SN - 0040-4039

VL - 32

SP - 3095

EP - 3098

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 26

ER -

Catalytic asymmetric addition of organolithiums to aldimines

Abstract

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