Catalytic asymmetric addition of organolithiums to aldimines

Kiyoshi Tomioka, Isao Inoue, Mitsuru Shindo, Kenji Koga

Research output: Contribution to journalArticlepeer-review

87 Citations (Scopus)


An asymmetric 1,2-addition of organolithiums to imines (1) was catalyzed by a substoichiometric amount (0.05-0.3 equivalent) of a chiral aminoether (2) to provide the corresponding optically active amines (3).

Original languageEnglish
Pages (from-to)3095-3098
Number of pages4
JournalTetrahedron Letters
Issue number26
Publication statusPublished - Jun 24 1991
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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