Cardiomyopathy secondary to systemic triglyceride storage disease

Fumio Terasaki; Keishiro Kawamura; Makoto Okabe; Tetsuya Hayashi; Hirofumi Deguchi; Shin Ichi Ando; Makoto Usui; Takahiro Matsumoto; Kensuke Egashira; Akira Takeshita

doi:10.1007/BF01545087

Cardiomyopathy secondary to systemic triglyceride storage disease

Fumio Terasaki, Keishiro Kawamura, Makoto Okabe, Tetsuya Hayashi, Hirofumi Deguchi, Shin Ichi Ando, Makoto Usui, Takahiro Matsumoto, Kensuke Egashira, Akira Takeshita

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Ultrastructural changes of a biopsied myocardium were observed by transmission electron microscopy in a patient with cardiomyopathy secondary to systemic triglyceride storage disease with Jordans' anomaly. There were many lipid droplets in the cardiocytes, and lipofuscin and mitochondria were increased. The volume fraction of myofibrils in the cardiocytes decreased because of an abundance of lipid droplets and mitochondriosis. Myocardial contractility may have been reduced by myofibrillar scarcity and low energy production resulting from an abnormality in the metabolism of fatty acids in the cardiocytes.

Original language	English
Pages (from-to)	88-91
Number of pages	4
Journal	Medical Molecular Morphology
Volume	30
Issue number	2
DOIs	https://doi.org/10.1007/BF01545087
Publication status	Published - 1997
Externally published	Yes

All Science Journal Classification (ASJC) codes

Pathology and Forensic Medicine
Molecular Biology

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10.1007/BF01545087

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title = "Cardiomyopathy secondary to systemic triglyceride storage disease",

abstract = "Ultrastructural changes of a biopsied myocardium were observed by transmission electron microscopy in a patient with cardiomyopathy secondary to systemic triglyceride storage disease with Jordans' anomaly. There were many lipid droplets in the cardiocytes, and lipofuscin and mitochondria were increased. The volume fraction of myofibrils in the cardiocytes decreased because of an abundance of lipid droplets and mitochondriosis. Myocardial contractility may have been reduced by myofibrillar scarcity and low energy production resulting from an abnormality in the metabolism of fatty acids in the cardiocytes.",

author = "Fumio Terasaki and Keishiro Kawamura and Makoto Okabe and Tetsuya Hayashi and Hirofumi Deguchi and Ando, {Shin Ichi} and Makoto Usui and Takahiro Matsumoto and Kensuke Egashira and Akira Takeshita",

year = "1997",

doi = "10.1007/BF01545087",

language = "English",

volume = "30",

pages = "88--91",

journal = "Medical Molecular Morphology",

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publisher = "Springer Japan",

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TY - JOUR

T1 - Cardiomyopathy secondary to systemic triglyceride storage disease

AU - Terasaki, Fumio

AU - Kawamura, Keishiro

AU - Okabe, Makoto

AU - Hayashi, Tetsuya

AU - Deguchi, Hirofumi

AU - Ando, Shin Ichi

AU - Usui, Makoto

AU - Matsumoto, Takahiro

AU - Egashira, Kensuke

AU - Takeshita, Akira

PY - 1997

Y1 - 1997

N2 - Ultrastructural changes of a biopsied myocardium were observed by transmission electron microscopy in a patient with cardiomyopathy secondary to systemic triglyceride storage disease with Jordans' anomaly. There were many lipid droplets in the cardiocytes, and lipofuscin and mitochondria were increased. The volume fraction of myofibrils in the cardiocytes decreased because of an abundance of lipid droplets and mitochondriosis. Myocardial contractility may have been reduced by myofibrillar scarcity and low energy production resulting from an abnormality in the metabolism of fatty acids in the cardiocytes.

AB - Ultrastructural changes of a biopsied myocardium were observed by transmission electron microscopy in a patient with cardiomyopathy secondary to systemic triglyceride storage disease with Jordans' anomaly. There were many lipid droplets in the cardiocytes, and lipofuscin and mitochondria were increased. The volume fraction of myofibrils in the cardiocytes decreased because of an abundance of lipid droplets and mitochondriosis. Myocardial contractility may have been reduced by myofibrillar scarcity and low energy production resulting from an abnormality in the metabolism of fatty acids in the cardiocytes.

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DO - 10.1007/BF01545087

M3 - Article

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SP - 88

EP - 91

JO - Medical Molecular Morphology

JF - Medical Molecular Morphology

IS - 2

ER -

Cardiomyopathy secondary to systemic triglyceride storage disease

Abstract

All Science Journal Classification (ASJC) codes

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