Calculation of metabolic flow of xylose in Lactococcus lactis

Hitomi Ohara, Michiko Owaki, Kenji Sonomoto

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


A circuit diagram is proposed on the basis of an analysis of metabolic pathways of lactic acid bacteria, namely, a phosphoketolase pathway and a pentose phosphate/glycolic pathway. An augmented matrix was derived from carbon balances and stoichiometries from the circuit diagram, and solved by Gaussian elimination. Results indicated that 70% of the amount of xylose was metabolized through the pentose phosphate/glycolic pathway and that the yield of lactic acid from xylose ranged from 0.34 to 0.52 (mol/mol), whereas that of pyruvic acid was more than 1.4 (mol/mol).

Original languageEnglish
Pages (from-to)92-94
Number of pages3
JournalJournal of Bioscience and Bioengineering
Issue number1
Publication statusPublished - Jan 2007

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology


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