Budd-Chiari syndrome and Epstein-Barr virus (EBV) associated plasmacytoma in a patient with chronic active EBV infection

S. Nagafuchi; H. Ishibashi; K. Anzai; K. Ohshima; Y. Ohno; N. Fukushima; M. Hashizume; K. Sugimachi; H. Chuman; M. Kikuchi; Y. Niho

doi:10.1007/BF00190746

Budd-Chiari syndrome and Epstein-Barr virus (EBV) associated plasmacytoma in a patient with chronic active EBV infection

S. Nagafuchi, H. Ishibashi, K. Anzai, K. Ohshima, Y. Ohno, N. Fukushima, M. Hashizume, K. Sugimachi, H. Chuman, M. Kikuchi, Y. Niho

Advanced Medical Intiatives

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Abstract

A 42-year-old Japanese man with chronic active Epstein-Barr virus (EBV) infection initially responded to treatment with interleukin-2 (IL-2). Six months later he developed thrombosis in the hepatic veins, and Budd-Chiari syndrome associated with severe hepatic damage was diagnosed. He also developed a solitary EBV-positive plasmacytoma in the right femur. Since these rare complications occurred after long-term IL-2 therapy, the possibility that long-term IL-2 therapy might cause Budd-Chiari syndrome and liver damage as well as EBV-associated plasmacytoma is discussed.

Original language	English
Pages (from-to)	883-886
Number of pages	4
Journal	The Clinical Investigator
Volume	72
Issue number	11
DOIs	https://doi.org/10.1007/BF00190746
Publication status	Published - Nov 1994

All Science Journal Classification (ASJC) codes

Medicine(all)

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10.1007/BF00190746

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title = "Budd-Chiari syndrome and Epstein-Barr virus (EBV) associated plasmacytoma in a patient with chronic active EBV infection",

abstract = "A 42-year-old Japanese man with chronic active Epstein-Barr virus (EBV) infection initially responded to treatment with interleukin-2 (IL-2). Six months later he developed thrombosis in the hepatic veins, and Budd-Chiari syndrome associated with severe hepatic damage was diagnosed. He also developed a solitary EBV-positive plasmacytoma in the right femur. Since these rare complications occurred after long-term IL-2 therapy, the possibility that long-term IL-2 therapy might cause Budd-Chiari syndrome and liver damage as well as EBV-associated plasmacytoma is discussed.",

author = "S. Nagafuchi and H. Ishibashi and K. Anzai and K. Ohshima and Y. Ohno and N. Fukushima and M. Hashizume and K. Sugimachi and H. Chuman and M. Kikuchi and Y. Niho",

year = "1994",

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T1 - Budd-Chiari syndrome and Epstein-Barr virus (EBV) associated plasmacytoma in a patient with chronic active EBV infection

AU - Nagafuchi, S.

AU - Ishibashi, H.

AU - Anzai, K.

AU - Ohshima, K.

AU - Ohno, Y.

AU - Fukushima, N.

AU - Hashizume, M.

AU - Sugimachi, K.

AU - Chuman, H.

AU - Kikuchi, M.

AU - Niho, Y.

PY - 1994/11

Y1 - 1994/11

N2 - A 42-year-old Japanese man with chronic active Epstein-Barr virus (EBV) infection initially responded to treatment with interleukin-2 (IL-2). Six months later he developed thrombosis in the hepatic veins, and Budd-Chiari syndrome associated with severe hepatic damage was diagnosed. He also developed a solitary EBV-positive plasmacytoma in the right femur. Since these rare complications occurred after long-term IL-2 therapy, the possibility that long-term IL-2 therapy might cause Budd-Chiari syndrome and liver damage as well as EBV-associated plasmacytoma is discussed.

AB - A 42-year-old Japanese man with chronic active Epstein-Barr virus (EBV) infection initially responded to treatment with interleukin-2 (IL-2). Six months later he developed thrombosis in the hepatic veins, and Budd-Chiari syndrome associated with severe hepatic damage was diagnosed. He also developed a solitary EBV-positive plasmacytoma in the right femur. Since these rare complications occurred after long-term IL-2 therapy, the possibility that long-term IL-2 therapy might cause Budd-Chiari syndrome and liver damage as well as EBV-associated plasmacytoma is discussed.

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Budd-Chiari syndrome and Epstein-Barr virus (EBV) associated plasmacytoma in a patient with chronic active EBV infection

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