Briarane diterpenes from two species of octocorals, Ellisella sp. and Pteroeides sp.

Chiaki Tanaka; Yumiko Yamamoto; Masahito Otsuka; Junichi Tanaka; Toshio Ichiba; Gerard Marriott; Rachmaniar Rachmat; Tatsuo Higa

doi:10.1021/np049923o

Briarane diterpenes from two species of octocorals, Ellisella sp. and Pteroeides sp.

Chiaki Tanaka, Yumiko Yamamoto, Masahito Otsuka, Junichi Tanaka, Toshio Ichiba, Gerard Marriott, Rachmaniar Rachmat, Tatsuo Higa

Research output: Contribution to journal › Article › peer-review

38 Citations (Scopus)

Abstract

Eight new briarane diterpenes (1-4, 7-10) have been isolated from two species of octocorals and the structures elucidated by spectroscopic analysis. Two diterpenes (2, 3) from the gorgonian Ellisella sp. inhibited cytokinesis, causing multinuclei formation on NBT-II cells, while a known briarane (12) from the sea pen Pteroeides sp. showed reversal of multidrug resistance.

Original language	English
Pages (from-to)	1368-1373
Number of pages	6
Journal	Journal of Natural Products
Volume	67
Issue number	8
DOIs	https://doi.org/10.1021/np049923o
Publication status	Published - Aug 2004
Externally published	Yes

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

Access to Document

10.1021/np049923o

Cite this

@article{24ee8a9ea59f44f6a1e42e8464b898f2,

title = "Briarane diterpenes from two species of octocorals, Ellisella sp. and Pteroeides sp.",

abstract = "Eight new briarane diterpenes (1-4, 7-10) have been isolated from two species of octocorals and the structures elucidated by spectroscopic analysis. Two diterpenes (2, 3) from the gorgonian Ellisella sp. inhibited cytokinesis, causing multinuclei formation on NBT-II cells, while a known briarane (12) from the sea pen Pteroeides sp. showed reversal of multidrug resistance.",

author = "Chiaki Tanaka and Yumiko Yamamoto and Masahito Otsuka and Junichi Tanaka and Toshio Ichiba and Gerard Marriott and Rachmaniar Rachmat and Tatsuo Higa",

year = "2004",

month = aug,

doi = "10.1021/np049923o",

language = "English",

volume = "67",

pages = "1368--1373",

journal = "Journal of Natural Products",

issn = "0163-3864",

publisher = "American Chemical Society",

number = "8",

}

TY - JOUR

T1 - Briarane diterpenes from two species of octocorals, Ellisella sp. and Pteroeides sp.

AU - Tanaka, Chiaki

AU - Yamamoto, Yumiko

AU - Otsuka, Masahito

AU - Tanaka, Junichi

AU - Ichiba, Toshio

AU - Marriott, Gerard

AU - Rachmat, Rachmaniar

AU - Higa, Tatsuo

PY - 2004/8

Y1 - 2004/8

N2 - Eight new briarane diterpenes (1-4, 7-10) have been isolated from two species of octocorals and the structures elucidated by spectroscopic analysis. Two diterpenes (2, 3) from the gorgonian Ellisella sp. inhibited cytokinesis, causing multinuclei formation on NBT-II cells, while a known briarane (12) from the sea pen Pteroeides sp. showed reversal of multidrug resistance.

AB - Eight new briarane diterpenes (1-4, 7-10) have been isolated from two species of octocorals and the structures elucidated by spectroscopic analysis. Two diterpenes (2, 3) from the gorgonian Ellisella sp. inhibited cytokinesis, causing multinuclei formation on NBT-II cells, while a known briarane (12) from the sea pen Pteroeides sp. showed reversal of multidrug resistance.

UR - http://www.scopus.com/inward/record.url?scp=4344600986&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=4344600986&partnerID=8YFLogxK

U2 - 10.1021/np049923o

DO - 10.1021/np049923o

M3 - Article

C2 - 15332856

AN - SCOPUS:4344600986

SN - 0163-3864

VL - 67

SP - 1368

EP - 1373

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 8

ER -

Briarane diterpenes from two species of octocorals, Ellisella sp. and Pteroeides sp.

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this