Bone related cell-stimulating scaffold materials and a 3D cellular construct for hard tissue regeneration

Osamu Suzuki; Takahisa Anada

doi:10.1007/978-4-431-55297-0_16

Bone related cell-stimulating scaffold materials and a 3D cellular construct for hard tissue regeneration

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The present article summarizes recently developed calcium phosphatebased scaffold materials that are capable of stimulating various cells involved in hard tissue formation as well as a method using newly developed cell culture devices to generate three dimensional (3D) cellular constructs. Synthetic octacalcium phosphate stimulates cellular functions of several cell types, including osteoblasts, chondrocytes, and pulp cells. The culture device promotes the easy assembly of chondrocytes in a 3D cellular construct. The scaffold materials, cellular constructs, and composite presented here are good candidates as implantable materials for the regeneration of hard tissue in bone defects depending on the severity of the tissue loss.

Original language	English
Title of host publication	Hyper Bio Assembler for 3D Cellular Systems
Publisher	Springer Japan
Pages	261-273
Number of pages	13
ISBN (Electronic)	9784431552970
ISBN (Print)	9784431552963
DOIs	https://doi.org/10.1007/978-4-431-55297-0_16
Publication status	Published - Jan 1 2015
Externally published	Yes

All Science Journal Classification (ASJC) codes

Engineering(all)
Medicine(all)
Immunology and Microbiology(all)
Biochemistry, Genetics and Molecular Biology(all)

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10.1007/978-4-431-55297-0_16

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title = "Bone related cell-stimulating scaffold materials and a 3D cellular construct for hard tissue regeneration",

abstract = "The present article summarizes recently developed calcium phosphatebased scaffold materials that are capable of stimulating various cells involved in hard tissue formation as well as a method using newly developed cell culture devices to generate three dimensional (3D) cellular constructs. Synthetic octacalcium phosphate stimulates cellular functions of several cell types, including osteoblasts, chondrocytes, and pulp cells. The culture device promotes the easy assembly of chondrocytes in a 3D cellular construct. The scaffold materials, cellular constructs, and composite presented here are good candidates as implantable materials for the regeneration of hard tissue in bone defects depending on the severity of the tissue loss.",

author = "Osamu Suzuki and Takahisa Anada",

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AU - Anada, Takahisa

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Y1 - 2015/1/1

N2 - The present article summarizes recently developed calcium phosphatebased scaffold materials that are capable of stimulating various cells involved in hard tissue formation as well as a method using newly developed cell culture devices to generate three dimensional (3D) cellular constructs. Synthetic octacalcium phosphate stimulates cellular functions of several cell types, including osteoblasts, chondrocytes, and pulp cells. The culture device promotes the easy assembly of chondrocytes in a 3D cellular construct. The scaffold materials, cellular constructs, and composite presented here are good candidates as implantable materials for the regeneration of hard tissue in bone defects depending on the severity of the tissue loss.

AB - The present article summarizes recently developed calcium phosphatebased scaffold materials that are capable of stimulating various cells involved in hard tissue formation as well as a method using newly developed cell culture devices to generate three dimensional (3D) cellular constructs. Synthetic octacalcium phosphate stimulates cellular functions of several cell types, including osteoblasts, chondrocytes, and pulp cells. The culture device promotes the easy assembly of chondrocytes in a 3D cellular construct. The scaffold materials, cellular constructs, and composite presented here are good candidates as implantable materials for the regeneration of hard tissue in bone defects depending on the severity of the tissue loss.

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PB - Springer Japan

ER -

Bone related cell-stimulating scaffold materials and a 3D cellular construct for hard tissue regeneration

Abstract

All Science Journal Classification (ASJC) codes

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