TY - JOUR
T1 - Bone bonding strength of diamond-structured porous titanium-alloy implants manufactured using the electron beam-melting technique
AU - Hara, Daisuke
AU - Nakashima, Yasuharu
AU - Sato, Taishi
AU - Hirata, Masanobu
AU - Kanazawa, Masayuki
AU - Kohno, Yusuke
AU - Yoshimoto, Kensei
AU - Yoshihara, Yusuke
AU - Nakamura, Akihiro
AU - Nakao, Yumiko
AU - Iwamoto, Yukihide
N1 - Funding Information:
Part of this research was supported by a Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science (No. 15 K10450 ) and Kyocera Medical Corporation. Three of the authors (Y.Y, A.N., and Y.N.) are employed by Kyocera Medical Corporation.
Publisher Copyright:
© 2015 Elsevier B.V. All rights reserved.
PY - 2016/2/1
Y1 - 2016/2/1
N2 - The present study examined the bone bonding strength of diamond-structured porous titanium-alloy (Porous-Ti-alloy) manufactured using the electron beam-melting technique in comparison with fiber mesh-coated or rough-surfaced implants. Cylindrical implants with four different pore sizes (500, 640, 800, and 1000 μm) of Porous-Ti-alloy, titanium fiber mesh (FM), and surfaces roughened by titanium arc spray (Ti-spray) were implanted into the distal femur of rabbits. Bone bonding strength and histological bone ingrowth were evaluated at 4 and 12 weeks after implantation. The bone bonding strength of Porous-Ti-alloy implants (640 μm pore size) increased over time from 541.4 N at 4 weeks to 704.6 N at 12 weeks and was comparable to that of FM and Ti-spray implants at both weeks. No breakage of the porous structure after mechanical testing was found with Porous-Ti-alloy implants. Histological bone ingrowth that increased with implantation time occurred along the inner structure of Porous-Ti-alloy implants. There was no difference in bone ingrowth in Porous-Ti-alloy implants with pore sizes among 500, 640, and 800 μm; however, less bone ingrowth was observed with the 1000 μm pore size. These results indicated Porous-Ti-alloy implants with pore size under 800 μm provided biologically active and mechanically stable surface for implant fixation to bone, and had potential advantages for weight bearing orthopedic implants such as acetabular cups.
AB - The present study examined the bone bonding strength of diamond-structured porous titanium-alloy (Porous-Ti-alloy) manufactured using the electron beam-melting technique in comparison with fiber mesh-coated or rough-surfaced implants. Cylindrical implants with four different pore sizes (500, 640, 800, and 1000 μm) of Porous-Ti-alloy, titanium fiber mesh (FM), and surfaces roughened by titanium arc spray (Ti-spray) were implanted into the distal femur of rabbits. Bone bonding strength and histological bone ingrowth were evaluated at 4 and 12 weeks after implantation. The bone bonding strength of Porous-Ti-alloy implants (640 μm pore size) increased over time from 541.4 N at 4 weeks to 704.6 N at 12 weeks and was comparable to that of FM and Ti-spray implants at both weeks. No breakage of the porous structure after mechanical testing was found with Porous-Ti-alloy implants. Histological bone ingrowth that increased with implantation time occurred along the inner structure of Porous-Ti-alloy implants. There was no difference in bone ingrowth in Porous-Ti-alloy implants with pore sizes among 500, 640, and 800 μm; however, less bone ingrowth was observed with the 1000 μm pore size. These results indicated Porous-Ti-alloy implants with pore size under 800 μm provided biologically active and mechanically stable surface for implant fixation to bone, and had potential advantages for weight bearing orthopedic implants such as acetabular cups.
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U2 - 10.1016/j.msec.2015.11.025
DO - 10.1016/j.msec.2015.11.025
M3 - Article
C2 - 26652463
AN - SCOPUS:84947709785
SN - 0928-4931
VL - 59
SP - 1047
EP - 1052
JO - Materials Science and Engineering C
JF - Materials Science and Engineering C
ER -