BODIPY-labeled fluorescent aptamer sensors for turn-on sensing of interferon-gamma and adenine compounds on cells

Akira Tsuchiya; Siti N. Hashim; Shoko Ise; Takafumi Furuhata; Kiyohiko Kawai; Rie Wakabayashi; Masahiro Goto; Noriho Kamiya; Shinsuke Sando

doi:10.2116/analsci.32.543

BODIPY-labeled fluorescent aptamer sensors for turn-on sensing of interferon-gamma and adenine compounds on cells

Akira Tsuchiya
, Siti N. Hashim
, Shoko Ise
, Takafumi Furuhata
, Kiyohiko Kawai
, Rie Wakabayashi
, Masahiro Goto
, Noriho Kamiya
, Shinsuke Sando

Applied Chemistry

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

An on-cell aptamer sensor has the potential to reveal cell-cell communications by signalling molecules. We attempted to design new fluorescent aptamer sensors for the sensing of IFN-? and adenine compounds on cells. BODIPY-labeled external quencher-free aptamer sensors have allowed a turn-on detection of the target molecule with improved off/on efficiency.

Original language	English
Pages (from-to)	543-547
Number of pages	5
Journal	analytical sciences
Volume	32
Issue number	5
DOIs	https://doi.org/10.2116/analsci.32.543
Publication status	Published - 2016

All Science Journal Classification (ASJC) codes

Analytical Chemistry

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10.2116/analsci.32.543

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abstract = "An on-cell aptamer sensor has the potential to reveal cell-cell communications by signalling molecules. We attempted to design new fluorescent aptamer sensors for the sensing of IFN-? and adenine compounds on cells. BODIPY-labeled external quencher-free aptamer sensors have allowed a turn-on detection of the target molecule with improved off/on efficiency.",

author = "Akira Tsuchiya and Hashim, \{Siti N.\} and Shoko Ise and Takafumi Furuhata and Kiyohiko Kawai and Rie Wakabayashi and Masahiro Goto and Noriho Kamiya and Shinsuke Sando",

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AU - Tsuchiya, Akira

AU - Hashim, Siti N.

AU - Ise, Shoko

AU - Furuhata, Takafumi

AU - Kawai, Kiyohiko

AU - Wakabayashi, Rie

AU - Goto, Masahiro

AU - Kamiya, Noriho

AU - Sando, Shinsuke

PY - 2016

Y1 - 2016

N2 - An on-cell aptamer sensor has the potential to reveal cell-cell communications by signalling molecules. We attempted to design new fluorescent aptamer sensors for the sensing of IFN-? and adenine compounds on cells. BODIPY-labeled external quencher-free aptamer sensors have allowed a turn-on detection of the target molecule with improved off/on efficiency.

AB - An on-cell aptamer sensor has the potential to reveal cell-cell communications by signalling molecules. We attempted to design new fluorescent aptamer sensors for the sensing of IFN-? and adenine compounds on cells. BODIPY-labeled external quencher-free aptamer sensors have allowed a turn-on detection of the target molecule with improved off/on efficiency.

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BODIPY-labeled fluorescent aptamer sensors for turn-on sensing of interferon-gamma and adenine compounds on cells

Abstract

All Science Journal Classification (ASJC) codes

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