Biodegradation or metabolism of bisphenol A: From microorganisms to mammals

Jeong Hun Kang; Yoshiki Katayama; Fusao Kondo

doi:10.1016/j.tox.2005.10.001

Biodegradation or metabolism of bisphenol A: From microorganisms to mammals

Jeong Hun Kang, Yoshiki Katayama, Fusao Kondo

Research output: Contribution to journal › Review article › peer-review

188 Citations (Scopus)

Abstract

Bisphenol A (BPA; 2,2-bis(4-hydroxyphenyl)propane; CAS Registry No. 80-05-7) is one of endocrine disruptors and is made by combining acetone and phenol. BPA can be metabolized by extensive organisms. In this review these BPA biodegradations or metabolisms by many organisms from microorganisms to mammals were referred. Though the metabolites of BPA can enhance estrogenicity or toxicity, generally, BPA metabolism by organisms leads to detoxication of BPA.

Original language	English
Pages (from-to)	81-90
Number of pages	10
Journal	Toxicology
Volume	217
Issue number	2-3
DOIs	https://doi.org/10.1016/j.tox.2005.10.001
Publication status	Published - Jan 16 2006

All Science Journal Classification (ASJC) codes

Toxicology

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10.1016/j.tox.2005.10.001

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abstract = "Bisphenol A (BPA; 2,2-bis(4-hydroxyphenyl)propane; CAS Registry No. 80-05-7) is one of endocrine disruptors and is made by combining acetone and phenol. BPA can be metabolized by extensive organisms. In this review these BPA biodegradations or metabolisms by many organisms from microorganisms to mammals were referred. Though the metabolites of BPA can enhance estrogenicity or toxicity, generally, BPA metabolism by organisms leads to detoxication of BPA.",

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AU - Kang, Jeong Hun

AU - Katayama, Yoshiki

AU - Kondo, Fusao

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Y1 - 2006/1/16

N2 - Bisphenol A (BPA; 2,2-bis(4-hydroxyphenyl)propane; CAS Registry No. 80-05-7) is one of endocrine disruptors and is made by combining acetone and phenol. BPA can be metabolized by extensive organisms. In this review these BPA biodegradations or metabolisms by many organisms from microorganisms to mammals were referred. Though the metabolites of BPA can enhance estrogenicity or toxicity, generally, BPA metabolism by organisms leads to detoxication of BPA.

AB - Bisphenol A (BPA; 2,2-bis(4-hydroxyphenyl)propane; CAS Registry No. 80-05-7) is one of endocrine disruptors and is made by combining acetone and phenol. BPA can be metabolized by extensive organisms. In this review these BPA biodegradations or metabolisms by many organisms from microorganisms to mammals were referred. Though the metabolites of BPA can enhance estrogenicity or toxicity, generally, BPA metabolism by organisms leads to detoxication of BPA.

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Biodegradation or metabolism of bisphenol A: From microorganisms to mammals

Abstract

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