Ba2+ current oscillation evoked by bradykinin in ras-transformed fibroblasts

Haruhiro Higashida, Naoto Hoshi, Minako Hashii, Tao Fu, Mami Noda, Yoshinori Nozawa

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

By voltage-clamp recording, we show a novel inward current which oscillates after activation with bradykinin or serum in v-Ki-ras-transformed NIH 3T3 cells. The current oscillation was infrequently observed in control NIH 3T3 fibroblasts. The same stimulation evokes Ca2+ oscillations in the ras-transformed cells but not in parental cells (Fu et al., FEBS Lett. 281, 263-266, 1991). The results suggest that the oscillatory currents are generated by influxes of divalent cations to maintain Ca2+ oscillations in ras-transformed NIH 3T3 cells.

Original languageEnglish
Pages (from-to)713-717
Number of pages5
JournalBiochemical and Biophysical Research Communications
Volume178
Issue number2
DOIs
Publication statusPublished - Jul 31 1991
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

Fingerprint

Dive into the research topics of 'Ba2+ current oscillation evoked by bradykinin in ras-transformed fibroblasts'. Together they form a unique fingerprint.

Cite this