Autoimmune cholangiopathy associated with rheumatoid arthritis

H. Ogata, H. Tsuji, M. Hashiguchi, K. Azuma, J. Shimono, M. Fujishima

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


We herein describe a patient with autoimmune cholangiopathy complicated with rheumatoid arthritis. A 58-year-old female was admitted to our hospital due to complications of arthralgia in her fingers, shoulders, elbows, knees and ankles. She presented with abnormally elevated levels of transaminases, alkaline phosphatase and was also negative for hepatitis B virus, hepatitis C virus and the serum mitochondrial antibody test, but had high titers of serum antinuclear antibody, rheumatoid factor and rheumatoid arthritis hemagglutination. A liver biopsy specimen showed chronic non-suppurative destructive cholangitis. She was thus diagnosed to have autoimmune cholangiopathy and rheumatoid arthritis. She began treatment with predonisolone 40mg per day. After 20 days of steroid therapy, her hepatic function tests improved and the arthralgia symptoms disappeared. This is, to our knowledge, the first case of autoimmune cholangiopathy associated with rheumatoid arthritis, in which both symptoms improved with steroid therapy.

Original languageEnglish
Pages (from-to)1533-1534
Number of pages2
Issue number36
Publication statusPublished - 2000

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology


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