Augmentation of antigen-specific cytotoxicity by concanavalin A at the peak of response to tumor allografts

Yoshinori Shimamoto; Kikuo Nomoto; Kazuto Taniguchi; Chiharu Kubo

doi:10.1016/0008-8749(79)90329-0

Augmentation of antigen-specific cytotoxicity by concanavalin A at the peak of response to tumor allografts

Yoshinori Shimamoto, Kikuo Nomoto, Kazuto Taniguchi, Chiharu Kubo

Research output: Contribution to journal › Article › peer-review

Abstract

Antigen-specific cytotoxicity was augmented 24 hr after in vivo or in vitro treatment with concanavalin A at approximately the peak of response to allografted EL-4 cells. Such augmentation appears to require protein synthesis but not cell division. The augmentation may be ascribed to enhanced expression of cytotoxic activity of performed effector T cells rather than an increase in the number of effector cells.

Original language	English
Pages (from-to)	204-210
Number of pages	7
Journal	Cellular Immunology
Volume	47
Issue number	1
DOIs	https://doi.org/10.1016/0008-8749(79)90329-0
Publication status	Published - Sept 15 1979
Externally published	Yes

All Science Journal Classification (ASJC) codes

Immunology

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10.1016/0008-8749(79)90329-0

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abstract = "Antigen-specific cytotoxicity was augmented 24 hr after in vivo or in vitro treatment with concanavalin A at approximately the peak of response to allografted EL-4 cells. Such augmentation appears to require protein synthesis but not cell division. The augmentation may be ascribed to enhanced expression of cytotoxic activity of performed effector T cells rather than an increase in the number of effector cells.",

author = "Yoshinori Shimamoto and Kikuo Nomoto and Kazuto Taniguchi and Chiharu Kubo",

note = "Funding Information: This work was supported by Grants-in-Aid Science and Culture and the Ministry of Health",

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AU - Shimamoto, Yoshinori

AU - Nomoto, Kikuo

AU - Taniguchi, Kazuto

AU - Kubo, Chiharu

N1 - Funding Information: This work was supported by Grants-in-Aid Science and Culture and the Ministry of Health

PY - 1979/9/15

Y1 - 1979/9/15

N2 - Antigen-specific cytotoxicity was augmented 24 hr after in vivo or in vitro treatment with concanavalin A at approximately the peak of response to allografted EL-4 cells. Such augmentation appears to require protein synthesis but not cell division. The augmentation may be ascribed to enhanced expression of cytotoxic activity of performed effector T cells rather than an increase in the number of effector cells.

AB - Antigen-specific cytotoxicity was augmented 24 hr after in vivo or in vitro treatment with concanavalin A at approximately the peak of response to allografted EL-4 cells. Such augmentation appears to require protein synthesis but not cell division. The augmentation may be ascribed to enhanced expression of cytotoxic activity of performed effector T cells rather than an increase in the number of effector cells.

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Augmentation of antigen-specific cytotoxicity by concanavalin A at the peak of response to tumor allografts

Abstract

All Science Journal Classification (ASJC) codes

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