Asymmetric Reduction of α-Methyl β-Keto Esters by Microbial Cells Immobilized with Prepolymer

Hiroyuki Akita; Hiroko Matsukura; Takeshi Oishi; Atsuo Tanaka; Kenji Sonomoto

doi:10.1248/cpb.35.4985

Asymmetric Reduction of α-Methyl β-Keto Esters by Microbial Cells Immobilized with Prepolymer

Hiroyuki Akita
, Hiroko Matsukura
, Takeshi Oishi
, Atsuo Tanaka
, Kenji Sonomoto

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Asymmetric reduction of a-methyl β-keto esters using microbial cells immobilized by the prepolymer method was examined. It was found that by a proper selection of the prepolymer in the stage of immobilization, the chemical and optical yields were both improved appreciably in some cases compared to those obtained by reduction with the native microorganisms.

Original language	English
Pages (from-to)	4985-4987
Number of pages	3
Journal	Chemical and Pharmaceutical Bulletin
Volume	35
Issue number	12
DOIs	https://doi.org/10.1248/cpb.35.4985
Publication status	Published - 1987
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Chemistry
Drug Discovery

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10.1248/cpb.35.4985

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title = "Asymmetric Reduction of α-Methyl β-Keto Esters by Microbial Cells Immobilized with Prepolymer",

abstract = "Asymmetric reduction of a-methyl β-keto esters using microbial cells immobilized by the prepolymer method was examined. It was found that by a proper selection of the prepolymer in the stage of immobilization, the chemical and optical yields were both improved appreciably in some cases compared to those obtained by reduction with the native microorganisms.",

author = "Hiroyuki Akita and Hiroko Matsukura and Takeshi Oishi and Atsuo Tanaka and Kenji Sonomoto",

year = "1987",

doi = "10.1248/cpb.35.4985",

language = "English",

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T1 - Asymmetric Reduction of α-Methyl β-Keto Esters by Microbial Cells Immobilized with Prepolymer

AU - Akita, Hiroyuki

AU - Matsukura, Hiroko

AU - Oishi, Takeshi

AU - Tanaka, Atsuo

AU - Sonomoto, Kenji

PY - 1987

Y1 - 1987

N2 - Asymmetric reduction of a-methyl β-keto esters using microbial cells immobilized by the prepolymer method was examined. It was found that by a proper selection of the prepolymer in the stage of immobilization, the chemical and optical yields were both improved appreciably in some cases compared to those obtained by reduction with the native microorganisms.

AB - Asymmetric reduction of a-methyl β-keto esters using microbial cells immobilized by the prepolymer method was examined. It was found that by a proper selection of the prepolymer in the stage of immobilization, the chemical and optical yields were both improved appreciably in some cases compared to those obtained by reduction with the native microorganisms.

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UR - https://www.scopus.com/pages/publications/84966063463#tab=citedBy

U2 - 10.1248/cpb.35.4985

DO - 10.1248/cpb.35.4985

M3 - Article

AN - SCOPUS:84966063463

SN - 0009-2363

VL - 35

SP - 4985

EP - 4987

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - 12

ER -

Asymmetric Reduction of α-Methyl β-Keto Esters by Microbial Cells Immobilized with Prepolymer

Abstract

All Science Journal Classification (ASJC) codes

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