Asymmetric [2,3]-Wittig Rearrangement Approach to the Formal Synthesis of (+)-Brefeldin A

Katsuhiko Tomooka, Katsuya Ishikawa, Takeshi Nakai

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


An asymmetric synthesis of the 2,4-disubstituted 1-cyclopentanal, a key precursor of brefeldin A, is described which involves as the key step an asymmetric [2,3]-Wittig rearrangement to control both the ring and side chain configurations.

Original languageEnglish
Pages (from-to)901-902
Number of pages2
Issue number9
Publication statusPublished - Sept 1995
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Organic Chemistry


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