TY - JOUR
T1 - Astroglial phagocytosis in central nervous system health and disease
AU - Yamasaki, Ryo
N1 - Funding Information:
This study was supported in part by a Health and Labor Sciences Research Grant on Intractable Diseases (H26-Nanchitou (Nan)-Ippan-074) from the Ministry of Health, Labor and Welfare, Japan; the Practical Research Project for Rare/Intractable Diseases from the Japan Agency for Medical Research and Development (AMED); “Glial Assembly” Grants-in-Aid for Scientific Research on Innovative Areas (MEXT KAKENHI Grant Numbers 25117001 and 25117012) from the Ministry of Education, Culture, Sports, Science and Technology of Japan; a Grant-in-Aid for Scientific Research (A) (JSPS KAKENHI Grant Number 16H02657); Grants-in-Aid for Scientific Research (C) (JSPS KAKENHI Grant Numbers 16K09694 and 26461295); a Grant-in-Aid for Exploratory Research (JSPS KAKENHI Grant Number 15K15341); and a Grant-in-Aid for Young Scientists (B) (JSPS KAKENHI Grant Number 15K19489) from the Japan Society for the Promotion of Science. We thank Ann Turnley, PhD, from Edanz Group (www.edanzediting.com/ac) for editing a draft of this manuscript.
Publisher Copyright:
© 2017 Japanese Society for Neuroimmunology
PY - 2017/11
Y1 - 2017/11
N2 - Phagocytosis by astrocytes is important in the developing brain and in central nervous system lesions. Astroglial phagocytosis usually contributes to the repair of damaged lesions, but, depending on the local milieu, astrocytes can become activated “A1” type astroglia, which release neurotoxic substances and accelerate regional damage.
AB - Phagocytosis by astrocytes is important in the developing brain and in central nervous system lesions. Astroglial phagocytosis usually contributes to the repair of damaged lesions, but, depending on the local milieu, astrocytes can become activated “A1” type astroglia, which release neurotoxic substances and accelerate regional damage.
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U2 - 10.1111/cen3.12413
DO - 10.1111/cen3.12413
M3 - Comment/debate
AN - SCOPUS:85034214937
SN - 1759-1961
VL - 8
SP - 285
EP - 286
JO - Clinical and Experimental Neuroimmunology
JF - Clinical and Experimental Neuroimmunology
IS - 4
ER -