Applications of aie to molecular recognition: Why is it superior to unimolecular recognition?

Takao Noguchi, Daisuke Yoshihara, Seiji Shinkai

Research output: Chapter in Book/Report/Conference proceedingChapter


Self-assembly has been utilized for the spontaneous formation of nanoarchitectures. Therein, a small change in the molecular structure dramatically alters the resulting macroscopic self-assembly morphologies and the consequent material properties. This macroscopic expression of the small initial difference via self-assembly can be alternatively regarded as precise translation of molecular structural information. In this chapter, we offer a novel molecular recognition concept utilizing self-assembly phenomena. A small difference in guest structures affords distinctly different self-assembly modes of fluorescent (FL) chemosensors and leads to their sensory responses characteristic of the guest structures. Thus, self-assembly has now been utilized as a FL sensory system for molecular recognition, particularly, of biologically important molecules and macromolecules. Through these studies, we wish to demonstrate why the AIE-based recognition is superior to that of unimolecule-based recognition.

Original languageEnglish
Title of host publicationPrinciples and Applications of Aggregation-Induced Emission
PublisherSpringer International Publishing
Number of pages27
ISBN (Electronic)9783319990378
ISBN (Print)9783319990361
Publication statusPublished - Oct 9 2018

All Science Journal Classification (ASJC) codes

  • Engineering(all)
  • Materials Science(all)
  • Biochemistry, Genetics and Molecular Biology(all)


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