Anionic hapten-antibody reactions on various cationic bilayer membrane systems

Hirotaka Ihara, Tomoaki Arimura, Takashi Imamura, Eiko Satoh, Toyoki Kunitake, Chuichi Hirayama

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Antigen-antibody reactions using Nα, Nε-bis(2,4-dinitrophenyl) l-lysine as an anionic hapten were examined in the presence of various cationic bilayer membranes. The turbidity change of the mixture provided information on the dispersion state of bilayer membranes. The degree of the turbidity change was closely related to the concentration of the haptens and the antibodies. In addition, the agglutination was remarkably dependent on the chemical structure of matrix amphiphiles, and there were two variants of the agglutination mode when the antigen-antibody reaction was examined at 35°C: one showed turbidity decrease with the hapten-antibody reaction and the other one did increase. According to DSC studies, the difference is attributable to different physical states resulting from the phase transition of matrix membranes.

Original languageEnglish
Pages (from-to)1017-1024
Number of pages8
JournalPolymer Journal
Issue number10
Publication statusPublished - Oct 1992

All Science Journal Classification (ASJC) codes

  • Polymers and Plastics
  • Materials Chemistry


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