Analytical chemistry and biochemistry of D-amino acids

Kazuhiro Imai, Takeshi Fukushima, Tomofumi Santa, Hiroshi Homma, Kenji Hamase, Kumiko Sakai, Masaru Kato

Research output: Contribution to journalReview articlepeer-review

113 Citations (Scopus)


The methodologies for the analysis of D-amino acids in biological materials have been reviewed, including the use of enzymes, gas and liquid chromatography with chiral stationary phases and diastereomer derivatization with chiral reagents followed by GC or HPLC separation. The distribution of D-amino acids in the body, their origin, metabolism and possible roles in human diseases are discussed.

Original languageEnglish
Pages (from-to)303-312
Number of pages10
JournalBiomedical Chromatography
Issue number6
Publication statusPublished - 1996
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry


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