An Overview on the Toxicological Properties of Ionic Liquids toward Microorganisms

Magaret Sivapragasam, Muhammad Moniruzzaman, Masahiro Goto

    Research output: Contribution to journalReview articlepeer-review

    57 Citations (Scopus)


    Ionic liquids (ILs), a class of materials with unique physicochemical properties, have been used extensively in the fields of chemical engineering, biotechnology, material sciences, pharmaceutics, and many others. Because ILs are very polar by nature, they can migrate into the environment with the possibility of inclusion in the food chain and bioaccumulation in living organisms. However, the chemical natures of ILs are not quintessentially biocompatible. Therefore, the practical uses of ILs must be preceded by suitable toxicological assessments. Among different methods, the use of microorganisms to evaluate IL toxicity provides many advantages including short generation time, rapid growth, and environmental and industrial relevance. This article reviews the recent research progress on the toxicological properties of ILs toward microorganisms and highlights the computational prediction of various toxicity models.

    Original languageEnglish
    Article number1900073
    JournalBiotechnology Journal
    Issue number4
    Publication statusPublished - Apr 1 2020

    All Science Journal Classification (ASJC) codes

    • Applied Microbiology and Biotechnology
    • Molecular Medicine


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