An expeditious synthesis of (3S,4S)-statine and (3S,4S)cyclohexylstatine

Yoshiji Takemoto, Teruyo Matsumoto, Yoshio Ito, Shiro Terashima

Research output: Contribution to journalArticlepeer-review

50 Citations (Scopus)


The title synthesis could be accomplished by employing highly stereoselective aldol reaction of O-methyl-O-trimethylsilyl ketene acetal with the (S)-α-amido aldehyde (2) in the presence of titanium (IV) chloride as a key step.

Original languageEnglish
Pages (from-to)217-218
Number of pages2
JournalTetrahedron Letters
Issue number2
Publication statusPublished - 1990

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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