Adipose-derived mesenchymal stem cells and regenerative medicine

Masamitsu Konno; Atsushi Hamabe; Shinichiro Hasegawa; Hisataka Ogawa; Takahito Fukusumi; Shimpei Nishikawa; Katsuya Ohta; Yoshihiro Kano; Miyuki Ozaki; Yuko Noguchi; Daisuke Sakai; Toshihiro Kudoh; Koichi Kawamoto; Hidetoshi Eguchi; Taroh Satoh; Masahiro Tanemura; Hiroaki Nagano; Yuichiro Doki; Masaki Mori; Hideshi Ishii

doi:10.1111/dgd.12049

Adipose-derived mesenchymal stem cells and regenerative medicine

Masamitsu Konno, Atsushi Hamabe, Shinichiro Hasegawa, Hisataka Ogawa, Takahito Fukusumi, Shimpei Nishikawa, Katsuya Ohta, Yoshihiro Kano, Miyuki Ozaki, Yuko Noguchi, Daisuke Sakai, Toshihiro Kudoh, Koichi Kawamoto, Hidetoshi Eguchi, Taroh Satoh, Masahiro Tanemura, Hiroaki Nagano, Yuichiro Doki, Masaki Mori, Hideshi Ishii

Surgery

Research output: Contribution to journal › Review article › peer-review

130 Citations (Scopus)

Abstract

Adipose tissue-derived mesenchymal stem cells (ADSCs) are multipotent and can differentiate into various cell types, including osteocytes, adipocytes, neural cells, vascular endothelial cells, cardiomyocytes, pancreatic β-cells, and hepatocytes. Compared with the extraction of other stem cells such as bone marrow-derived mesenchymal stem cells (BMSCs), that of ADSCs requires minimally invasive techniques. In the field of regenerative medicine, the use of autologous cells is preferable to embryonic stem cells or induced pluripotent stem cells. Therefore, ADSCs are a useful resource for drug screening and regenerative medicine. Here we present the methods and mechanisms underlying the induction of multilineage cells from ADSCs.

Original language	English
Pages (from-to)	309-318
Number of pages	10
Journal	Development Growth and Differentiation
Volume	55
Issue number	3
DOIs	https://doi.org/10.1111/dgd.12049
Publication status	Published - Apr 2013

All Science Journal Classification (ASJC) codes

Developmental Biology
Cell Biology

Access to Document

10.1111/dgd.12049

Cite this

Konno, M., Hamabe, A., Hasegawa, S., Ogawa, H., Fukusumi, T., Nishikawa, S., Ohta, K., Kano, Y., Ozaki, M., Noguchi, Y., Sakai, D., Kudoh, T., Kawamoto, K., Eguchi, H., Satoh, T., Tanemura, M., Nagano, H., Doki, Y., Mori, M., & Ishii, H. (2013). Adipose-derived mesenchymal stem cells and regenerative medicine. Development Growth and Differentiation, 55(3), 309-318. https://doi.org/10.1111/dgd.12049

Konno, M, Hamabe, A, Hasegawa, S, Ogawa, H, Fukusumi, T, Nishikawa, S, Ohta, K, Kano, Y, Ozaki, M, Noguchi, Y, Sakai, D, Kudoh, T, Kawamoto, K, Eguchi, H, Satoh, T, Tanemura, M, Nagano, H, Doki, Y, Mori, M & Ishii, H 2013, 'Adipose-derived mesenchymal stem cells and regenerative medicine', Development Growth and Differentiation, vol. 55, no. 3, pp. 309-318. https://doi.org/10.1111/dgd.12049

@article{21dd0105d464480da157236c19d26756,

title = "Adipose-derived mesenchymal stem cells and regenerative medicine",

abstract = "Adipose tissue-derived mesenchymal stem cells (ADSCs) are multipotent and can differentiate into various cell types, including osteocytes, adipocytes, neural cells, vascular endothelial cells, cardiomyocytes, pancreatic β-cells, and hepatocytes. Compared with the extraction of other stem cells such as bone marrow-derived mesenchymal stem cells (BMSCs), that of ADSCs requires minimally invasive techniques. In the field of regenerative medicine, the use of autologous cells is preferable to embryonic stem cells or induced pluripotent stem cells. Therefore, ADSCs are a useful resource for drug screening and regenerative medicine. Here we present the methods and mechanisms underlying the induction of multilineage cells from ADSCs.",

author = "Masamitsu Konno and Atsushi Hamabe and Shinichiro Hasegawa and Hisataka Ogawa and Takahito Fukusumi and Shimpei Nishikawa and Katsuya Ohta and Yoshihiro Kano and Miyuki Ozaki and Yuko Noguchi and Daisuke Sakai and Toshihiro Kudoh and Koichi Kawamoto and Hidetoshi Eguchi and Taroh Satoh and Masahiro Tanemura and Hiroaki Nagano and Yuichiro Doki and Masaki Mori and Hideshi Ishii",

year = "2013",

month = apr,

doi = "10.1111/dgd.12049",

language = "English",

volume = "55",

pages = "309--318",

journal = "Development Growth and Differentiation",

issn = "0012-1592",

publisher = "Wiley-Blackwell",

number = "3",

}

TY - JOUR

T1 - Adipose-derived mesenchymal stem cells and regenerative medicine

AU - Konno, Masamitsu

AU - Hamabe, Atsushi

AU - Hasegawa, Shinichiro

AU - Ogawa, Hisataka

AU - Fukusumi, Takahito

AU - Nishikawa, Shimpei

AU - Ohta, Katsuya

AU - Kano, Yoshihiro

AU - Ozaki, Miyuki

AU - Noguchi, Yuko

AU - Sakai, Daisuke

AU - Kudoh, Toshihiro

AU - Kawamoto, Koichi

AU - Eguchi, Hidetoshi

AU - Satoh, Taroh

AU - Tanemura, Masahiro

AU - Nagano, Hiroaki

AU - Doki, Yuichiro

AU - Mori, Masaki

AU - Ishii, Hideshi

PY - 2013/4

Y1 - 2013/4

N2 - Adipose tissue-derived mesenchymal stem cells (ADSCs) are multipotent and can differentiate into various cell types, including osteocytes, adipocytes, neural cells, vascular endothelial cells, cardiomyocytes, pancreatic β-cells, and hepatocytes. Compared with the extraction of other stem cells such as bone marrow-derived mesenchymal stem cells (BMSCs), that of ADSCs requires minimally invasive techniques. In the field of regenerative medicine, the use of autologous cells is preferable to embryonic stem cells or induced pluripotent stem cells. Therefore, ADSCs are a useful resource for drug screening and regenerative medicine. Here we present the methods and mechanisms underlying the induction of multilineage cells from ADSCs.

AB - Adipose tissue-derived mesenchymal stem cells (ADSCs) are multipotent and can differentiate into various cell types, including osteocytes, adipocytes, neural cells, vascular endothelial cells, cardiomyocytes, pancreatic β-cells, and hepatocytes. Compared with the extraction of other stem cells such as bone marrow-derived mesenchymal stem cells (BMSCs), that of ADSCs requires minimally invasive techniques. In the field of regenerative medicine, the use of autologous cells is preferable to embryonic stem cells or induced pluripotent stem cells. Therefore, ADSCs are a useful resource for drug screening and regenerative medicine. Here we present the methods and mechanisms underlying the induction of multilineage cells from ADSCs.

UR - http://www.scopus.com/inward/record.url?scp=84876082200&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84876082200&partnerID=8YFLogxK

U2 - 10.1111/dgd.12049

DO - 10.1111/dgd.12049

M3 - Review article

C2 - 23452121

AN - SCOPUS:84876082200

SN - 0012-1592

VL - 55

SP - 309

EP - 318

JO - Development Growth and Differentiation

JF - Development Growth and Differentiation

IS - 3

ER -

Adipose-derived mesenchymal stem cells and regenerative medicine

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this