Acute myelitis associated with hyperIgEemia and atopic dermatitis

Jun ichi Kira, Kenji Yamasaki, Yuji Kawano, Takuro Kobayashi

Research output: Contribution to journalArticlepeer-review

68 Citations (Scopus)


We herein describe 4 adult patients with upper cervical myelitis presenting with paresthesia in the distal parts of all four limbs and who also all had hyperIgEemia. Two of them had full-blown atopic dermatitis at the time of neurologic illness, while the others had a preceding history of atopic dermatitis. All showed high signal intensity lesions at either the C3 or C4 segment, which mainly affected the posterior column on the T2-weighted spinal cord magnetic resonance imaging. All patients had specific IgE antibodies to two mite antigens and their onset of myelitis coincided with the seasonal increase of the mite antigens in Japan. Therefore, it is possible that the atopic conditions with hyperIgEemia in these patients may thus have contributed to the development of myelitis.

Original languageEnglish
Pages (from-to)199-203
Number of pages5
JournalJournal of the Neurological Sciences
Issue number2
Publication statusPublished - May 29 1997

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology


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