TY - JOUR
T1 - Acute and Chronic Effects of Cancer Drugs on the Cardiovascular System
AU - Moriyama, Shohei
AU - Fukata, Mitsuhiro
AU - Kusaba, Hitoshi
AU - Maruyama, Toru
AU - Akashi, Koichi
N1 - Funding Information:
Sources of Funding: This work was supported by JSPS KAKENHI Grant Number JP17K11577 .
Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2020/4
Y1 - 2020/4
N2 - Several cancer treatments cause cardiotoxicity that can lead to heart failure, coronary artery disease, arrhythmia, and pericardial disease. In this review, representative cases of heart failure following cardiotoxicity caused by trastuzumab, anthracycline, and hematopoietic stem cell transplantation are described with case notes. Additionally, other important points regarding cardiotoxicity related to heart failure are reported. During and after potentially cardiotoxic therapy, periodic cardiac examinations are recommended to detect any cardiovascular disorders; these are ameliorated if appropriately diagnosed at an earlier stage. It is important for cardiologists and oncologists to understand the pathophysiology of representative cardiovascular disease cases following cancer treatment.
AB - Several cancer treatments cause cardiotoxicity that can lead to heart failure, coronary artery disease, arrhythmia, and pericardial disease. In this review, representative cases of heart failure following cardiotoxicity caused by trastuzumab, anthracycline, and hematopoietic stem cell transplantation are described with case notes. Additionally, other important points regarding cardiotoxicity related to heart failure are reported. During and after potentially cardiotoxic therapy, periodic cardiac examinations are recommended to detect any cardiovascular disorders; these are ameliorated if appropriately diagnosed at an earlier stage. It is important for cardiologists and oncologists to understand the pathophysiology of representative cardiovascular disease cases following cancer treatment.
UR - http://www.scopus.com/inward/record.url?scp=85079170222&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85079170222&partnerID=8YFLogxK
U2 - 10.1016/j.hfc.2019.11.002
DO - 10.1016/j.hfc.2019.11.002
M3 - Review article
C2 - 32143767
AN - SCOPUS:85079170222
SN - 1551-7136
VL - 16
SP - 231
EP - 241
JO - Heart Failure Clinics
JF - Heart Failure Clinics
IS - 2
ER -
