Acetaminophen-induced acute pancreatitis. A case report

Hisato Igarashi, Tetuhide Ito, Masahiro Yoshinaga, Takamasa Oono, Hiroyuki Sakai, Ryoichi Takayanagi

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


Context: Drug-induced acute pancreatitis is rare but should not be overlooked in a patient who presents with idiopathic acute pancreatitis. More than 100 drugs have been implicated in causing the disease: acetaminophen has been associated with acute pancreatitis in cases where there has been an overdose of drugs; however, the frequency is rare. Case report: We report the case of a 35-year-old woman who presented with acute pancreatitis and severe metabolic acidosis after overdosing on a drug containing acetaminophen. She improved dramatically after intensive care; however, she showed recurrent episodes after re-overdosing on the same drug. With her self re-challenge test, she was diagnosed as having acetaminophen-induced pancreatitis and metabolic acidosis. A review of the relevant literature is also presented. Conclusions: Drug-induced acute pancreatitis is often challenging for clinicians and a detailed mechanism is unknown. It is very important to rule out drug-induced pancreatitis when treating pancreatitis with an unknown etiology.

Original languageEnglish
Pages (from-to)550-553
Number of pages4
JournalJournal of the Pancreas
Issue number5
Publication statusPublished - 2009

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Endocrinology


Dive into the research topics of 'Acetaminophen-induced acute pancreatitis. A case report'. Together they form a unique fingerprint.

Cite this