A stereoselective synthesis of cyclohexylnorstatine, the key component of a renin inhibitor

Teruyo Matsumoto; Yuko Kobayashi; Yoshiji Takemoto; Yoshio Ito; Tetsuhide Kamijo; Hiromu Harada; Shiro Terashima

doi:10.1016/S0040-4039(00)97574-9

A stereoselective synthesis of cyclohexylnorstatine, the key component of a renin inhibitor

Teruyo Matsumoto, Yuko Kobayashi, Yoshiji Takemoto, Yoshio Ito, Tetsuhide Kamijo, Hiromu Harada, Shiro Terashima

Organic and Biological Chemistry

Research output: Contribution to journal › Article › peer-review

51 Citations (Scopus)

Abstract

The title synthesis could be accomplished by employing the novel addition reaction of a Grignard reagent with an imine in the presence of cerium(III) chloride.

Original language	English
Pages (from-to)	4175-4176
Number of pages	2
Journal	Tetrahedron Letters
Volume	31
Issue number	29
DOIs	https://doi.org/10.1016/S0040-4039(00)97574-9
Publication status	Published - 1990

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)97574-9

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title = "A stereoselective synthesis of cyclohexylnorstatine, the key component of a renin inhibitor",

abstract = "The title synthesis could be accomplished by employing the novel addition reaction of a Grignard reagent with an imine in the presence of cerium(III) chloride.",

author = "Teruyo Matsumoto and Yuko Kobayashi and Yoshiji Takemoto and Yoshio Ito and Tetsuhide Kamijo and Hiromu Harada and Shiro Terashima",

year = "1990",

doi = "10.1016/S0040-4039(00)97574-9",

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volume = "31",

pages = "4175--4176",

journal = "Tetrahedron Letters",

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T1 - A stereoselective synthesis of cyclohexylnorstatine, the key component of a renin inhibitor

AU - Matsumoto, Teruyo

AU - Kobayashi, Yuko

AU - Takemoto, Yoshiji

AU - Ito, Yoshio

AU - Kamijo, Tetsuhide

AU - Harada, Hiromu

AU - Terashima, Shiro

PY - 1990

Y1 - 1990

N2 - The title synthesis could be accomplished by employing the novel addition reaction of a Grignard reagent with an imine in the presence of cerium(III) chloride.

AB - The title synthesis could be accomplished by employing the novel addition reaction of a Grignard reagent with an imine in the presence of cerium(III) chloride.

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U2 - 10.1016/S0040-4039(00)97574-9

DO - 10.1016/S0040-4039(00)97574-9

M3 - Article

AN - SCOPUS:0025283995

SN - 0040-4039

VL - 31

SP - 4175

EP - 4176

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 29

ER -

A stereoselective synthesis of cyclohexylnorstatine, the key component of a renin inhibitor

Abstract

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