Abstract
A solid-phase synthesis of heterocyclic β-turn mimetics of sialyl Lewis X, which is a natural carbohydrate ligand of selectins, was established. This synthetic method could be very useful for drug discovery of selectin antagonists using combinatorial chemistry techniques. (C) 2000 Elsevier Science Ltd. All rights reserved.
Original language | English |
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Pages (from-to) | 1827-1830 |
Number of pages | 4 |
Journal | Bioorganic and Medicinal Chemistry Letters |
Volume | 10 |
Issue number | 16 |
DOIs | |
Publication status | Published - Aug 21 2000 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Molecular Medicine
- Molecular Biology
- Pharmaceutical Science
- Drug Discovery
- Clinical Biochemistry
- Organic Chemistry