A simple model of cell proliferation of bacteria using min oscillation

Hidetsugu Sakaguchi, Yuka Kawasaki

Research output: Contribution to journalArticlepeer-review

Abstract

A mathematical model of Min oscillation in Escherichia coli is numerically studied. The oscillatory state and hysteretic transition are explained with simpler coupled differential equations. Next, we propose a simple model of cell growth and division using the Min oscillation. The cell cycle is not constant but exhibits fluctuation in the deterministic model. Finally, we perform direct numerical simulation of cell assemblies composed of many cells obeying the simple growth and division model. As the cell number increases with time, the spatial distribution of cell assembly becomes more circular, although the cells are aligned almost in the x-direction.

Original languageEnglish
Article number104002
Journaljournal of the physical society of japan
Volume88
Issue number10
DOIs
Publication statusPublished - 2019

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

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